Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Intracellular
Group enriched (Extravillous trophoblasts, Syncytiotrophoblasts, Cytotrophoblasts, Hofbauer cells, Cardiomyocytes)
Low immune cell specificity
Low cell line specificity
Homodimer (PubMed:23609930). Part of a multisubunit complex that groups tRNA ligases for Arg (RARS1), Asp (DARS1), Gln (QARS1), Ile (IARS1), Leu (LARS1), Lys (KARS1), Met (MARS1) the bifunctional ligase for Glu and Pro (EPRS1) and the auxiliary subunits AIMP1/p43, AIMP2/p38 and EEF1E1/p18 (PubMed:19131329, PubMed:19289464).
Aminoacyl-tRNA synthetase, Ligase
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For Research Use Only. Not For Clinical Use.