Transcription factors
Intracellular
Cell type enriched (Inhibitory neurons)
Not detected in immune cells
Cell line enhanced (AN3-CA, U-138 MG, WM-115)
Interacts with SMAD4 (via homeobox DNA-binding domain) (PubMed:14671321). Interacts (via homeobox DNA-binding domain) with POU4F2; this interaction suppresses DLX1-mediated transcriptional activity in postnatal retina and enhances retinal ganglion cell (RGC) differentiation (By similarity).
Activator, Developmental protein, DNA-binding, Repressor
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For Research Use Only. Not For Clinical Use.