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FLT1
Enables ATP binding activity; growth factor binding activity; and vascular endothelial growth factor-activated receptor activity. Involved in several processes, including liver regeneration; negative regulation of vascular endothelial growth factor production; and positive regulation of cell population proliferation. Located in extracellular space and plasma membrane. Used to study corneal neovascularization. Biomarker of breast cancer; diabetic retinopathy; liver cirrhosis; myocardial infarction; and vascular dementia. Human ortholog(s) of this gene implicated in Kuhnt-Junius degeneration; diabetic retinopathy; and pre-eclampsia. Orthologous to human FLT1 (fms related receptor tyrosine kinase 1).
Related Diseases
Rheumatoid Arthritis
- A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer (MHC-CN0676)
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- Class: Class I
- Antigen: FLT1
- Antigen Species: Human
- Peptide: TLFWLLTL
- Conjugate: Unconjugated
- FITC-A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer (MHC-CN0675)
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- Class: Class I
- Antigen: FLT1
- Antigen Species: Human
- Peptide: TLFWLLTL
- Conjugate: FITC
- APC-A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer (MHC-CN0674)
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- Class: Class I
- Antigen: FLT1
- Antigen Species: Human
- Peptide: TLFWLLTL
- Conjugate: APC
- A*02:01/Human VEGFR1 (GVLLWEIFSL) MHC Pentamer (MHC-YF771)
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- Class: Class I
- Antigen: VEGFR1
- Antigen Species: Human
- Peptide: GVLLWEIFSL
- Conjugate: Unlabeled, Biotin, R-PE, APC
- PE-A*02:01/Human FLT1 (TLFWLLTL) MHC Tetramer (MHC-CN0673)
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- Class: Class I
- Antigen: FLT1
- Antigen Species: Human
- Peptide: TLFWLLTL
- Conjugate: PE
- PE-A*24:02/Human FLT1 (SYGVLLWEI) MHC Tetramer (MHC-CN1412)
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- Class: Class I
- Antigen: FLT1
- Antigen Species: Human
- Peptide: SYGVLLWEI
- Conjugate: PE
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For Research Use Only. Not For Clinical Use.