Disease related genes, Human disease related genes
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Homodimer and homotetramer in solution. Identified in the spliceosome C complex. Interacts with KMT5B (via C-terminus). Interacts (via N-terminus) with KPNA2 and NXF1/TAP. Interacts with F-actin with a stoichiometry of 2:1. Interacts with GARIN3, SMN1 and PABPN1 (PubMed:17103222).
Actin-binding, RNA-binding
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For Research Use Only. Not For Clinical Use.