GAD2

Predicted to enable glutamate binding activity; glutamate decarboxylase activity; and pyridoxal phosphate binding activity. Predicted to be involved in glutamate decarboxylation to succinate. Predicted to act upstream of or within neurotransmitter biosynthetic process. Located in axon; cytoplasm; and synapse. Is expressed in several structures, including genitourinary system; gut; heart; nervous system; and sensory organ. Used to study epilepsy and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in gestational diabetes; schizophrenia; and type 1 diabetes mellitus. Orthologous to human GAD2 (glutamate decarboxylase 2).