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ID4

This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner.
Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Endometrial ciliated cells, Muller glia cells, Smooth muscle cells, Endometrial stromal cells, Glandular and luminal cells, Breast myoepithelial cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, AN3-CA, EFO-21, HEK93, SCLC-21H, SuSa)

Interaction

Heterodimer with other HLH proteins.

Molecular function

Repressor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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