Transporters
Intracellular
Cell type enhanced (Oligodendrocyte precursor cells, Peritubular cells, Excitatory neurons, Leydig cells)
Not detected in immune cells
Cell line enhanced (A-431, BJ hTERT+, hTERT-RPE1, RPTEC TERT1, U-138 MG)
Binds to DNA as a homomultimer. Dimerization is induced by binding to calcium (PubMed:17962406). Interacts with the C-terminus of PSEN1 and PSEN2 and with PSEN2 CTF subunit. Associates with KCN1. Component of heteromultimeric potassium channels. Identified in potassium channel complexes containing KCND1, KCND2, KCND3, KCNIP1, KCNIP2, KCNIP3, KCNIP4, DPP6 and DPP10 (By similarity). Interacts with KCND2 and KCND3.
Ion channel, Potassium channel, Repressor, Voltage-gated channel
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For Research Use Only. Not For Clinical Use.