Intracellular
Cell type enhanced (Cardiomyocytes, Extravillous trophoblasts, Adipocytes, Cytotrophoblasts, Hofbauer cells, Fibroblasts, Syncytiotrophoblasts, Smooth muscle cells)
Low immune cell specificity
Low cell line specificity
Interacts with the BATF-JUNB heterodimer. Interacts with BATF (via bZIP domain); the interaction is direct (By similarity). Interacts with SPIB and DEF6. Directly interacts with NLRP3 in the nucleus of Th2 cells; this interaction enhances IRF4 ability to bind to the IL4 promoter and is required for optimal IRF4-dependent IL4 transcription (By similarity).
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For Research Use Only. Not For Clinical Use.