Intracellular
Group enriched (Inhibitory neurons, Oligodendrocyte precursor cells)
Not detected in immune cells
Cell line enhanced (AF22, SH-SY5Y, U-2197)
Binds PPP1CA and/or PPP1CC. Binds F-actin in an ATP-sensitive manner. Interacts with ACOT9, ARHGAP26 and PIK3R2. Interacts with components of the WAVE1 complex, CYFIP1 and NCKAP1; this interaction mediates PI3K-WAVE1 association and actin cytoskeleton remodeling (By similarity). Interacts with KIRREL3 (PubMed:25902260).
Actin-binding, Motor protein, Myosin
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For Research Use Only. Not For Clinical Use.