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NES
Predicted to enable CCR5 chemokine receptor binding activity. Acts upstream of or within cell projection morphogenesis; negative regulation of neuron apoptotic process; and nervous system development. Located in cytoplasm and intermediate filament. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; foregut-midgut junction; and metanephros. Orthologous to human NES (nestin).
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Cardiomyocytes, Endothelial cells, Sertoli cells, Adipocytes, Smooth muscle cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, HUVEC TERT2, LHCN-M2, RH-30, SuSa, WM-115)
Interaction
Forms homodimers and homotetramers in vitro. In mixtures with other intermediate filament proteins such as vimentin and alpha-internexin, tis protein preferentially forms heterodimers which can assemble to form intermediate filaments if nestin does not exceed 25%. Interacts with FHOD3 (By similarity).
Molecular function
Developmental protein
More Types Infomation
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IF, IHC
- Mouse Anti-NES Recombinant Antibody (clone 28C6) (MOB-1670z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IHC, IP
- Rabbit Anti-NES Polyclonal Antibody (MRO-2064-CN) (MRO-2064-CN)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: IHC
- Rabbit Anti-NES Polyclonal Antibody (MRO-2065-CN) (MRO-2065-CN)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: IF, IHC, FC, WB
- Rabbit Anti-NES Recombinant Antibody (clone AFY0079) (MOR-0108-FY)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IHC, WB
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, IP WB
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC-P, WB
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
- Chicken Anti-Nes Polyclonal IgY (BRD-0721MZ)
-
- Species Reactivity: Human, Rat, Mouse
- Type: Chicken antibody
- Application: ICC/IF, IHC, WB
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IF, IHC-Fr, IHC-P, WB, FC, IHC
-
- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, IF, IHC-Fr, IHC-P, WB, FC, IHC
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IHC, IF, FC
- Mouse Anti-NES Recombinant Antibody (clone 3H12C8) (VS3-XY1155)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
- Rabbit Anti-NES Recombinant Antibody (VS3-CJ983) (VS3-CJ983)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IF, IHC
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, IP
- Mouse Anti-NES Recombinant Antibody (clone 3H12B9) (VS3-XY1154)
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, FC
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