Plasma proteins, Transporters
Secreted
Cell type enhanced (Adipocytes, Fibroblasts, Smooth muscle cells, Endothelial cells)
Group enriched (eosinophil, neutrophil)
Cell line enhanced (BJ hTERT+, hTERT-RPE1, U-2197)
Interacts with FBLN1. Interacts (via CTCK domain) with NOTCH1 (via the EGF-like repeat region) (PubMed:12050162). Interacts with GJA1/CX43 (PubMed:15181016, PubMed:15213231). Interacts with ITGA5:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB5 (PubMed:12695522, PubMed:15611078). Interacts with ZDHHC22; the interaction may lead to CCN3 palmitoylation (By similarity).
Growth factor
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For Research Use Only. Not For Clinical Use.