Human disease related genes
Intracellular
Cell type enhanced (Excitatory neurons, Inhibitory neurons, Rod photoreceptor cells, Cone photoreceptor cells, Oligodendrocyte precursor cells, Bipolar cells)
Not detected in immune cells
Cell line enhanced (Daudi, RT4, SCLC-21H, SuSa, U-2 OS)
Interacts with RAB3A and RAB3B that have been activated by GTP-binding. Interacts with RAB3C, RAB3D and RAB26. Interacts with TSPOAP1 and RIMBP2. Interacts with PPFIA3 and PPFIA4. Interacts via its zinc finger with the first C2 domain of UNC13A. Forms a complex consisting of UNC13A, RIMS2 and RAB3A. Heterodimer with PCLO. Part of a ternary complex involving PCLO and EPAC2 (By similarity).
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For Research Use Only. Not For Clinical Use.