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STEAP1
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.
Protein class
Cancer-related genes, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Basal respiratory cells, Prostatic glandular cells, Club cells, Theca cells, Urothelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, CAPAN-2, U-138 MG)
Molecular function
Oxidoreductase
More Types Infomation
- PE-A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer (MHC-CN1233)
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- Class: Class I
- Antigen: STEAP1
- Antigen Species: Human
- Peptide: MLAVFLPIV
- Conjugate: PE
- APC-A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer (MHC-CN1234)
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- Class: Class I
- Antigen: STEAP1
- Antigen Species: Human
- Peptide: MLAVFLPIV
- Conjugate: APC
- FITC-A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer (MHC-CN1235)
-
- Class: Class I
- Antigen: STEAP1
- Antigen Species: Human
- Peptide: MLAVFLPIV
- Conjugate: FITC
- A*02:01/Human STEAP1 (MLAVFLPIV) MHC Tetramer (MHC-CN1236)
-
- Class: Class I
- Antigen: STEAP1
- Antigen Species: Human
- Peptide: MLAVFLPIV
- Conjugate: Unconjugated
- APC-H-2Db/Human STEAP (VSKINRTEM) MHC Tetramer (MHC-CN0339)
-
- Class: Class I
- Antigen: STEAP
- Antigen Species: Human
- Peptide: VSKINRTEM
- Conjugate: APC
- PE-H-2Db/Human STEAP (VSKINRTEM) MHC Tetramer (MHC-CN0340)
-
- Class: Class I
- Antigen: STEAP
- Antigen Species: Human
- Peptide: VSKINRTEM
- Conjugate: PE
-
- Species Reactivity: Human
- Application: WB
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Inhib
- Mouse Anti-STEAP1 Recombinant Antibody (HPAB-1208WJ) (HPAB-1208WJ)
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, Inhib
-
- Target: STEAP1
- Linker: mc-val-cit-PABC (cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Thio-Anti-STEAP1-MC-vc-PAB-MMAE ADC (ADC-157LCT)
-
- Target: STEAP1
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-Human STEAP1 Recombinant Antibody (TAB-586CL)
-
- Species Reactivity: Human
- Type: Antibody
- Anti-STEAP-1 (clone 120v.24)-MC-MMAF ADC (ADC-175CL)
-
- Target: STEAP-1
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-STEAP-1 (clone 120v.24)-MC-vc-PAB-MMAE ADC (ADC-174CL)
-
- Target: STEAP-1
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-STEAP-1 (clone 120)-MC-vc-PAB-MMAE ADC (ADC-173CL)
-
- Target: STEAP-1
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Human Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-0489-YJ-S(P)) (HPAB-0489-YJ-S(P))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC, ELISA
- Mouse Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-0488-YJ-S(P)) (HPAB-0488-YJ-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC, ELISA
- Mouse Anti-STEAP1 Recombinant Antibody; scFv Fragment (HPAB-0487-YJ-S(P)) (HPAB-0487-YJ-S(P))
-
- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: FC, ELISA
- Human Anti-STEAP1 Recombinant Antibody; Fab Fragment (HPAB-N0259-YC-F(E)) (HPAB-N0259-YC-F(E))
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
- Human Anti-STEAP1 Recombinant Antibody (HPAB-0489-YJ) (HPAB-0489-YJ)
-
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1
- Application: FC, ELISA
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For Research Use Only. Not For Clinical Use.