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VEGFB
Enables identical protein binding activity. Acts upstream of or within cardiac muscle contraction; coronary vasculature development; and protein O-linked glycosylation. Located in extracellular region. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and musculoskeletal system. Human ortholog(s) of this gene implicated in myocardial infarction and pulmonary hypertension. Orthologous to human VEGFB (vascular endothelial growth factor B).
Protein class
Cancer-related genes, FDA approved drug targets, RAS pathway related proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Cardiomyocytes, Muller glia cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Low cell line specificity
Interaction
Homodimer; disulfide-linked. Can also form heterodimer with VEGF.
Molecular function
Growth factor, Heparin-binding, Mitogen
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, IF, IHC
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC-P, WB
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.