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KRT17

This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008]
Protein class

Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Group enriched (Basal prostatic cells, Urothelial cells, Prostatic glandular cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (hTCEpi, SiHa)

Interaction

Heterodimer of a type I and a type II keratin. KRT17 associates with KRT6 isomers (KRT6A or KRT6B). Interacts with TRADD and SFN (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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