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MAP3K10
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Horizontal cells, Excitatory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Low cell line specificity
Interaction
Homodimer. Interacts with SH3RF2.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
Related Diseases
Endometrial Cancer
Throid Cancer
- Chicken Anti-MAP3K10 Polyclonal IgY (BRD-0757MZ)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: ELISA, WB
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For Research Use Only. Not For Clinical Use.