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PUS1
This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Monomer (PubMed:23707380, 24722331). Forms a complex with RARG and the SRA1 RNA in the nucleus (By similarity).
Molecular function
Isomerase
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: FC, ICC/IF, IHC-P, WB
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- Species Reactivity: Human, Hamster, Rat
- Type: Rabbit IgG
- Application: WB, IF, IP
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For Research Use Only. Not For Clinical Use.