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Anti-Aβ Intrabody [+36GFP] (IAB-B052(G))

Recombinant anti-Aβ intrabody in fusion with +36GFP works within cells and is directed against amyloidogenic protein fragment Aβ, expressed in 293T cells. Intrabodies have shown efficacy in blocking the toxicity of Aβ in cell culture and paving the way for clinical trials of these reagents in brain disorders.      

Specifications
Immunogen
human Amyloid beta
Host
human
Type
scFv-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Neutralization; Functional studies
Target
Alternative Names
Amyloid beta; Aβ; Abeta

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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