Anti-ADAM17 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Anti-TACE (ADAM17) antibodies are disclosed that for the first time in the art are capable of binding to TACE, of acting as antagonists of one or more its biological activities, in particular by binding to TACE in a cross domain binding mode in which residues in both the catalytic domain and in the cysteine rich/disintegrin domains (Dis-Cys) are involved in antibody binding to TACE, helping to improve the specificity of the antibody binding and/or helping to improve inhibition of TACE biological activity. The therapeutic uses of the antibodies, in particular for the treatment of cancer are disclosed.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-38 | Recombinant Anti-human ADAM17 Antibody | ELISA, WB, FC, FuncS | IgG |
MHH-38 | Recombinant Human Anti-human ADAM17 Antibody | ELISA, IP, FuncS | IgG |
MOB-0437MZ | Mouse Anti-ADAM17 Recombinant Antibody (clone 1F6) | FC, IF, IHC-P, WB | Mouse IgG |
MRO-0030-CN | Rabbit Anti-ADAM17 Recombinant Antibody (clone JM10-35) | WB, IF, IP, FC | Rabbit IgG |
ZG-0529J | Rabbit Anti-ADAM17 Recombinant Antibody (clone 5A1) | ELISA, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-38-F(E) | Recombinant Anti-human ADAM17 Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
MHH-38-F(E) | Recombinant Human Anti-human ADAM17 Antibody Fab Fragment | ELISA, WB, IF, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-38-S(P) | Recombinant Anti-human ADAM17 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
MHH-38-S(P) | Recombinant Human Anti-human ADAM17 Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0444CL | Anti-Human ADAM17 Recombinant Antibody (ml022C3) | ELISA, Inhib, FuncS | |
TAB-0444CL-S(P) | Anti-Human ADAM17 Recombinant Antibody scFv Fragment (ml022C3) | ELISA, Inhib, FuncS | |
TAB-0444CL-F(E) | Anti-Human ADAM17 Recombinant Antibody Fab Fragment (ml022C3) | ELISA, Inhib, FuncS |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0445CL | Anti-Human ADAM17 Recombinant Antibody (cl022C3) | ELISA, Inhib, FuncS | Chimeric (mouse/human) |
TAB-0445CL-S(P) | Anti-Human ADAM17 Recombinant Antibody scFv Fragment (cl022C3) | ELISA, Inhib, FuncS | Chimeric (mouse/human) |
TAB-0445CL-F(E) | Anti-Human ADAM17 Recombinant Antibody Fab Fragment (cl022C3) | ELISA, Inhib, FuncS | Chimeric (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0446CL | Anti-Human ADAM17 Recombinant Antibody (hzl022C3) | ELISA, Inhib, FuncS | Humanized Antibody |
TAB-0446CL-S(P) | Anti-Human ADAM17 Recombinant Antibody scFv Fragment (hzl022C3) | ELISA, Inhib, FuncS | Humanized Antibody |
TAB-0446CL-F(E) | Anti-Human ADAM17 Recombinant Antibody Fab Fragment (hzl022C3) | ELISA, Inhib, FuncS | Humanized Antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0447CL | Anti-Human ADAM17 Recombinant Antibody (hl022C3) | ELISA, Inhib, FuncS | Human antibody |
TAB-0447CL-S(P) | Anti-Human ADAM17 Recombinant Antibody scFv Fragment (hl022C3) | ELISA, Inhib, FuncS | Human antibody |
TAB-0447CL-F(E) | Anti-Human ADAM17 Recombinant Antibody Fab Fragment (hl022C3) | ELISA, Inhib, FuncS | Human antibody |
TAB-0669CLV | Anti-Human ADAM17 Recombinant Antibody (D1(A12)) | ELISA, PK, Inhib, IHC | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0070 | Hi-Affi™ Rabbit Anti-ADAM17 Recombinant Antibody (clone DS70AB) | WB, IF, IP, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0393 | PE-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer | FCM, IHC | |
MHC-CN0394 | APC-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer | FCM, IHC | |
MHC-CN0395 | FITC-A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer | FCM, IHC | |
MHC-CN0396 | A*02:01/Human ADAM17 (YLIELIDRV) MHC Tetramer | FCM, IHC | |
MHC-YF732 | A*02:01/Human TACE (YLIELIDRV) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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