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Anti-AXL scFv (TAB-0336CL-S(P))

The Anti-AXL antibody is an full mouse monoclonal antibody that specifically bind to anexelekto, which is a receptor tyrosine kinase and is said to be responsible for signal transduction to downstream molecules through its autophosphorylation and involved in cell growth enhancement, suppression of apoptosis, cell migration, and cell adhesion. The AXL-specific antibody herein can exert an angiogenesis-suppressive effect and an antitumor effect by inhibiting phosphporylation activity of AXL, and therefore be used in the treatment of cancers such as pancreatic Adenocarcinoma and breast Cancer.      

Specifications
Host
Mouse
Specificity
Human
Species Reactivity
Cross-react with mouse AXL
Related Disease
Pancreatic Adenocarcinoma, Breast Cancer
Target
Alternative Names
AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7
Entrez Gene ID
558
UniProt ID
P30530

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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