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Anti-CASP3 Intrabody [+36GFP] (IAB-B002(G))

Recombinant anti-CASP3 intrabody in fusion with +36GFP works within cells and specifically binds to pro-apoptotic protein CASP3, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.      

Specifications
Immunogen
human caspase 3, apoptosis-related cysteine peptidase
Host
llama
Type
vhh-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Antibody assay: Immunocytochemistry; Neutralization; Functional studies
Target
Alternative Names
CASP3; caspase 3, apoptosis-related cysteine peptidase; CPP32; SCA-1; CPP32B; caspase-3; CASP-3; CPP-32
Entrez Gene ID
836
UniProt ID
P42574

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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