Products

Anti-CD18 Immunocytokine, GMP140-IgG (mAb 60.3) (ACFP-SH163)

This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-CD18 IgG to GMP140. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the CD18 as well as the biological activity of GMP140. This mAb is highly regarded among anti-CD18 antibodies in its ability to inhibit a plethora of leukocyte functions. This immunocytokine was designed for treating inhibit a plethora of leukocyte functions.      

Specifications
Target
CD18
Molecule Class
GMP140-IgG2
Species Reactivity
Human
Host
Chimeric (Human-Mouse)
Expression Host
CHO
Clone
mAb 60.3
Related Disease
Leukocyte functions inhibition
Cytokines 1
GMP140
Cytokines 1 Description
P-selectin is a protein that in humans is encoded by the SELP gene. P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules. Other names for P-selectin include CD62P, Granule Membrane Protein 140 (GMP-140), and Platelet Activation-Dependent Granule to External Membrane Protein (PADGEM).
Cytokine 1 Species
Human
Applications
This product can be used therapeutically to deliver biologically active ligands to a desired tissue.
Target
Alternative Names
ITGB2; integrin; beta 2; complement component 3 receptor 3 and 4 subunit; LAD; CD18; MF17; MFI7
Entrez Gene ID
3689
UniProt ID
P05107

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Send Inquiry Now!
Name:
* Phone:
* E-mail Address:
* Service & Products Interested:
Project Description:
* Verification Code:
Please input "biolabs"(case insensitive) as verification code.
Contact Us to Order
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-871-5806    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2017 Creative-Biolabs All Rights Reserved