Recombinant monoclonal antibody to CEACAM5. A5B7 is a mouse monoclonal antibody that can be potentially used in the treatment of cancer.
Figure 1 Mean (± SE) plasma concentration−time profiles of total platinum (s) and following iv bolus administration of cisplatin, CMdextran−cisplatin, A5B −CMdextran−cisplatin, A5B7−CMdextran−cisplatin, A5B7−CMdextran, and A5B7.
Mcintosh, D. P., Cooke, R. J., Mclachlan, A. J., Daley‐Yates, P. T., & Rowland, M. (1997). Pharmacokinetics and tissue distribution of cisplatin and conjugates of cisplatin with carboxymethyldextran and A5B7 monoclonal antibody in CD1 mice. Journal of pharmaceutical sciences, 86(12), 1478-1483.
Figure 2 Mean (± SE) concentration−time profiles of platinum (s) and ¹²⁵I (---)in kidney following iv bolus administration of cisplatin, CMdextran−cisplatin, A5B7−CMdextran−cisplatin, [¹²⁵I]A5B7−CMdextran−cisplatin, [¹²⁵I]A5B7−CMdextran, and A5B7.
Mcintosh, D. P., Cooke, R. J., Mclachlan, A. J., Daley‐Yates, P. T., & Rowland, M. (1997). Pharmacokinetics and tissue distribution of cisplatin and conjugates of cisplatin with carboxymethyldextran and A5B7 monoclonal antibody in CD1 mice. Journal of pharmaceutical sciences, 86(12), 1478-1483.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-703 | Anti-Human CEACAM5 Recombinant Antibody (Altumomab) | IF, IP, Neut, FuncS, ELISA, FC, IHC | IgG1 |
TAB-418LC-F(E) | Anti-Human CEACAM5 Recombinant Antibody Fab Fragment (COL-Human 9) | FC, WB | |
TAB-419LC-F(E) | Anti-Human CEACAM5 Recombinant Antibody Fab Fragment (COL-Human 12) | FC, WB | |
TAB-420LC-F(E) | Anti-Human CEACAM5 Recombinant Antibody Fab Fragment (COL-Human 13) | FC, WB | |
TAB-421LC-F(E) | Anti-Human CEACAM5 Recombinant Antibody Fab Fragment (COL-Human 15) | FC, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L003E | anti-CEACAM5 immunotoxin BDI-1 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L003R | anti-CEACAM5 immunotoxin BDI-1 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L004E | anti-CEACAM5 immunotoxin BDI-1 (scFv)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L004R | anti-CEACAM5 immunotoxin BDI-1 (scFv)-RTA | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-409LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-409LC) | SPR, ELISA, FC | Humanized antibody |
TAB-412LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-412LC) | ELISA, FC | Chimeric (Mouse/Human) IgG1 |
TAB-409LC-F(E) | Human Anti-CEACAM5 Recombinant Antibody; Fab Fragment (TAB-409LC-F(E)) | SPR, ELISA, FC | Humanized Fab |
TAB-412LC-F(E) | Human Anti-CEACAM5 Recombinant Antibody; Fab Fragment (TAB-412LC-F(E)) | FC, ELISA | Chimeric (Mouse/Human) Fab |
TAB-413LC-F(E) | Human Anti-CEACAM5 Recombinant Antibody; Fab Fragment (TAB-413LC-F(E)) | FC, ELISA | Chimeric (Mouse/Human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-410LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-410LC) | ELISA | Humanized antibody |
TAB-414LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-414LC) | ELISA, FC, Inhib | Human IgG1 |
TAB-415LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-415LC) | ELISA, FC, Inhib | Human IgG1 |
TAB-416LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-416LC) | ELISA, FC, Inhib | Human IgG1 |
TAB-417LC | Human Anti-CEACAM5 Recombinant Antibody (TAB-417LC) | ELISA, FuncS, IF | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-411LC-S(P) | Human Anti-Human CEACAM5 Recombinant Antibody scFv Fragment | ELISA | Human antibody |
TAB-411LC-F(E) | Human Anti-Human CEACAM5 Recombinant Antibody Fab Fragment | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-002LC-VHH | Anti-Human CEACAM5 Recombinant Antibody(VHH library) | SPR, FC, ELISA | Single domain antibody |
HPAB-0204-FY | Recombinant llama Anti-CEACAM5 Antibody (HPAB-0204-FY) | ADCC, ELISA | llama VHH |
HPAB-0205-FY | Recombinant llama Anti-CEACAM5 Antibody (HPAB-0205-FY) | ADCC, E | llama VHH |
HPAB-0206-FY | Recombinant llama Anti-CEACAM5 Antibody (HPAB-0206-FY) | ADCC, E | llama VHH |
HPAB-1024WJ | Recombinant Camelid Anti-CEACAM5 Single Domain Antibody | SPR, Inhib | Camelid VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0089MZ | Recombinant Mouse Anti-Carcinoembryonic antigen Antibody (clone A9203) | ELISA | Mouse antibody |
HPAB-0348-YJ | Mouse Anti-CEACAM5 Recombinant Antibody (clone 10E1) | ELISA, IHC | Mouse IgG1 |
VS-0323-XY5 | Human Anti-CEACAM5 Recombinant Antibody (clone αCEA4-8A) | ELISA | Human IgG |
VS3-WK1656 | Recombinant Mouse Anti-CEACAM5 Capture Antibody (clone 15A12) | ELISA | Mouse IgG1 |
VS3-WK1657 | Recombinant Mouse Anti-CEACAM5 Detection Antibody (clone 9H4) | ELISA | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0118MZ | Chicken Anti-CEACAM5 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0649 | Hi-Affi™ Rabbit Anti-CEACAM5 Recombinant Antibody (clone DS649AB) | IHC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC1991 | PE-DR7/Human CEACAM5 (QRLLLTASLLTFWNP) MHC Tetramer | FCM | |
MHC-LC1992 | PE-DR1/Human CEACAM5 (QRLLLTASLLTFWNP) MHC Tetramer | FCM | |
MHC-LC1993 | PE-DR8/Human CEACAM5 (TFWNPPTTAKLTIES) MHC Tetramer | FCM | |
MHC-YF053 | DRB1*04:01/Human CEA (YACFVSNLATGRNNS) MHC Monomer | MHC Multimer | |
MHC-YF059 | DRB1*04:05/Human CEA (LWWVNNQSLPVSP) MHC Monomer | MHC Multimer |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0155-FY-S(P) | Mouse Anti-CEACAM5 Recombinant Antibody; scFv Fragment (HPAB-0155-FY-S(P)) | Activ | Humanized scFv |
HPAB-0243-FY-S(P) | Mouse Anti-CEACAM5 Recombinant Antibody (clone M5A); scFv Fragment | ELISA | Mouse scFv |
HPAB-0348-YJ-S(P) | Mouse Anti-CEACAM5 Recombinant Antibody (clone 10E1); scFv Fragment | ELISA, IHC | Mouse scFv |
HPAB-1094WJ-S(P) | Mouse Anti-CEACAM5 Recombinant Antibody; scFv Fragment (HPAB-1094WJ-S(P)) | ELISA, FC | Mouse scFv |
HPAB-2106-FY-S(P) | Human Anti-CEACAM5 Recombinant Antibody (clone CEA6); scFv Fragment | ELISA, FC, Inhib | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0155-FY-F(E) | Mouse Anti-CEACAM5 Recombinant Antibody; Fab Fragment (HPAB-0155-FY-F(E)) | Activ | Humanized Fab |
HPAB-0243-FY-F(E) | Human Anti-CEACAM5 Recombinant Antibody (clone M5A); Fab Fragment | ELISA | Chimeric (mouse/human) Fab |
HPAB-0348-YJ-F(E) | Mouse Anti-CEACAM5 Recombinant Antibody (clone 10E1); Fab Fragment | ELISA, IHC | Mouse Fab |
HPAB-1094WJ-F(E) | Mouse Anti-CEACAM5 Recombinant Antibody; Fab Fragment (HPAB-1094WJ-F(E)) | ELISA, FC | Mouse Fab |
HPAB-2106-FY-F(E) | Human Anti-CEACAM5 Recombinant Antibody (clone CEA6); Fab Fragment | ELISA, FC, Inhib | Human Fab, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-703 | Afuco™ Anti-CEACAM5 ADCC Recombinant Antibody (Altumomab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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