Recombinant Mouse Anti-DERP1 Antibody (4C1) (CAT#: PABC-206)
Recombinant Mouse Antibody (4C1) is capable of binding to DERP1, expressed in Chinese Hamster Ovary cells (CHO). This antibody partially inhibits IgE antibody binding to Der p1, suggesting that the epitopes for 4C1 and human IgE antibodies overlap.
Specific Inquiry
Neut
Figure 1 Mouse Anti-DERP1 Antibody (4C1) in Neut.
Effect of mutations in epitopes for mAb 4C1, 5H8 and 10B9 on IgE antibody binding to group 1 mite allergens by inhibition assays . Reduction of IgE antibody binding to multiple epitope mutants versus the wild type, using pooled plasma from mite allergic patients (n = 4). Inhibitors are the Der p 1-mAb 4C1 epitope triple mutant and the Der p 1-mAb 5H8 epitope quadruple mutant.
Glesner, J., Vailes, L. D., Schlachter, C., Mank, N., Minor, W., Osinski, T., ... & Pomés, A. (2017). Antigenic determinants of Der p 1: specificity and cross-reactivity associated with IgE antibody recognition. The Journal of Immunology, 198(3), 1334-1344.
ELISA
Figure 2 Mouse Anti-DERP1 Antibody (4C1) in ELISA.
Antibody binding analysis of pro-rDer p 1 mutants. ELISA dose-response curves of the mAb 4C1 mutants compared with pro-rDer p 1, rDer p 1, and nDer p 1 using either biotinylated mAb 4C1.
Chruszcz, M., Pomés, A., Glesner, J., Vailes, L. D., Osinski, T., Porebski, P. J., ... & Chapman, M. D. (2012). Molecular determinants for antibody binding on group 1 house dust mite allergens. Journal of Biological Chemistry, 287(10), 7388-7398.
Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native DERP1
- Species Reactivity
- D. pteronyssinus
- Clone
- 4C1
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
- Alternative Names
- Der p1; Peptidase 1; DERP1; D. pteronyssinus
- UniProt ID
- P08176
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-060 | Recombinant Mouse Anti-D. pteronyssinus DerP1 Antibody (10B9) | WB, ELISA, FuncS | IgG |
| PABC-227 | Recombinant Mouse Anti-DERP1 Antibody (5H8) | WB | IgG |
| HPAB-0068-WJ | Recombinant Mouse Anti-DERP1 Antibody (W108) | ELISA, FC, Inhib, Block, WB, IHC | Mouse IgG2b |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-060 | Recombinant Mouse Anti-D. pteronyssinus DerP1 Antibody scFv Fragment (10B9) | WB, ELISA, FuncS | scFv |
| PFBC-206 | Recombinant Mouse Anti-DERP1 Antibody Fab Fragment (4C1) | ELISA | Fab |
| PFBC-227 | Recombinant Mouse Anti-DERP1 Antibody Fab Fragment (5H8) | WB | Fab |
| HPAB-0068-WJ-S(P) | Recombinant Mouse Anti-DERP1 Antibody scFv Fragment (W108) | ELISA, FC | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-060 | Recombinant Mouse Anti-D. pteronyssinus DerP1 Antibody Fab Fragment (10B9) | WB, ELISA, FuncS | Fab |
| PSBC-206 | Recombinant Mouse Anti-DERP1 Antibody scFv Fragment (4C1) | ELISA | scFv |
| PSBC-227 | Recombinant Mouse Anti-DERP1 Antibody scFv Fragment (5H8) | WB | scFv |
| HPAB-0068-WJ-F(E) | Recombinant Mouse Anti-DERP1 Antibody Fab Fragment (W108) | ELISA, FC | Mouse Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-047 | Recombinant Mouse Anti-Derp1 Antibody (5H8) | WB, ELISA, FuncS, Inhib | IgG |
| PABX-047-F (E) | Recombinant Mouse Anti-Derp1 Antibody Fab Fragment (5H8) | WB, ELISA, FuncS | Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-047-S (P) | Recombinant Mouse Anti-Derp1 Antibody scFv Fragment (5H8) | WB, ELISA, FuncS | scFv |
MHC Tetramer for Other Applications
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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