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Zolimomab aritox (TAB-884)

Recombinant mouse monoclonal antibody scFv fragment expressed in E. Coli binding to human CD5. Zolimomab aritox is a mouse monoclonal antibody which has been investigated for the treatment of systemic lupus erythematosus and graft-versus-host disease, but the studies failed to show positive effects of the drug.It is an anti-CD5 antibody which is linked to the A chain of the ricin protein.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
IgG1
Species Reactivity
Human
Applications
Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, ICC and most other immunological methods.
CAS NO.
141483-72-9
Generic Name
Zolimomab aritox
Related Disease
Graft-versus-host disease (GvHD)
Target
Alternative Names
Zolimomab aritox; 141483-72-9; H65-RTA; XomaZyme-H65; CD5; CD5 molecule; CD5 antigen (p56 62) , LEU1; T-cell surface glycoprotein CD5
Entrez Gene ID
921
UniProt ID
P06127

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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