Anti-Human MUC16 Recombinant Antibody F(ab')2 Fragment( Igovomab) (CAT#: TAB-043)
Recombinant antibody F(ab')2 fragment Fabto MUC16. Indium (111In) igovomab (trade name Indimacis-125) was a mouse monoclonal antibody for the diagnosis of ovarian cancer.
Linked to the chelating agent DTPA and labelled with Indium-111, it was used for imaging (radio-immuno scintigraphy) of the cancer. The drug is no longer available.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cervix
(Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65600/166228_B_7_3.jpg
(Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65600/166228_B_7_3.jpg
Figure 2 RNA cell line category: Group enriched (A-431, HeLa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
Figure 2 RNA cell line category: Group enriched (A-431, HeLa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- F(ab')2 - G1
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, IHC and most other immunological methods.
- Trade name
- indimacis-125
- CAS
- 171656-50-1
- Generic Name
- Igovomab
- Related Disease
- Ovarian cancers
Product Property
- Purity
- >95.0% as determined by analysis by RP-HPLC.
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
- Alternative Names
- Igovomab;indimacis-125;171656-50-1;Indimacis-125;Indium (111In) igovomab;MUC16;mucin 16, cell surface associated;mucin-16;CA125;FLJ14303;CA-125;MUC-16;CA125 ovarian cancer antigen;ovarian carcinoma antigen CA125;ovarian cancer-related tumor marker CA125;
- Gene ID
- 94025
- UniProt ID
- Q8WXI7
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MUC16"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1301z | Mouse Anti-MUC16 Recombinant Antibody (clone 21C12) | WB, ELISA, IHC | Mouse IgG |
| MOB-0268MZ | Recombinant Mouse Anti-Human Mucin 16 Cell Surface Associated Antibody (clone N12) | IHC | Mouse antibody |
| HPAB-0120LY | Mouse Anti-MUC16 Recombinant Antibody (HPAB-0120LY) | WB, ELISA, FC, IHC | Mouse IgG |
| MRO-1040-CN | Recombinant Rabbit Anti-MUC16 Monoclonal Antibody (CBACN-386) | WB, IF, FC | Rabbit IgG |
| MRO-1041-CN | Recombinant Rabbit Anti-MUC16 Monoclonal Antibody (CBACN-387) | WB, IF, FC | Rabbit IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0339CL | Human Anti-MUC16 Recombinant Antibody (TAB-0339CL) | DB, WB, IP, ELISA, FC, CDC | Humanized Antibody |
| TAB-1397CL | Human Anti-MUC16 Recombinant Antibody (TAB-1397CL) | FuncS | Humanized IgG |
| TAB-1399CL | Human Anti-MUC16 Recombinant Antibody (TAB-1399CL) | FuncS | Humanized IgG |
| TAB-1397CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1397CL-S(P)) | FuncS | Humanized scFv |
| TAB-1399CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1399CL-S(P)) | FuncS | Humanized scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1398CL | Human Anti-MUC16 Recombinant Antibody (TAB-1398CL) | FuncS | Chimeric (mouse/human) IgG |
| TAB-1400CL | Human Anti-MUC16 Recombinant Antibody (TAB-1400CL) | FuncS | Chimeric (mouse/human) IgG |
| TAB-1398CL-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1398CL-S(P)) | FuncS | Mouse scFv |
| TAB-1398CL-F(E) | Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1398CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| TAB-1400CL-F(E) | Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1400CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1401CL | Anti-Human MUC16 Recombinant Antibody (OC125) | IF, IHC, IP, FC | |
| TAB-1402CL | Anti-Human MUC16 Recombinant Antibody (VK-8) | IF, FC | |
| TAB-1401CL-S(P) | Anti-Human MUC16 Recombinant Antibody scFv Fragment (OC125) | IF, IHC, IP, FC | |
| TAB-1402CL-S(P) | Anti-Human MUC16 Recombinant Antibody scFv Fragment (VK-8) | IF, FC | |
| TAB-1401CL-F(E) | Anti-Human MUC16 Recombinant Antibody Fab Fragment (OC125) | IF, IHC, IP, FC |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2321 | Hi-Affi™ Recombinant Rabbit Anti-MUC16 Monoclonal Antibody (DS2321AB) | ICC, IHC-P, WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0310-YC-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0310-YC-S(P)) | ELISA, FC, IHC, FuncS | Mouse scFv |
| FAMAB-0043-YC-S(P) | Mouse Anti-MUC16 Recombinant Antibody (clone 196-14); scFv Fragment | FuncS | Mouse scFv |
| FAMAB-0044-YC-S(P) | Mouse Anti-MUC16 Recombinant Antibody (clone ch196-14); scFv Fragment | FuncS | Mouse scFv |
| HPAB-0120LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0120LY-S(P)) | WB, ELISA, FC, IHC | Mouse scfv |
| HPAB-0121LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0121LY-S(P)) | WB, ELISA, FC, IHC | Mouse scfv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0043-YC-F(E) | Mouse Anti-MUC16 Recombinant Antibody (clone 196-14); Fab Fragment | FuncS | Mouse Fab |
| FAMAB-0044-YC-F(E) | Human Anti-MUC16 Recombinant Antibody (clone ch196-14); Fab Fragment | FuncS | Human Fab |
| HPAB-1114LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1114LY-F(E)) | ELISA | Mouse Fab |
| HPAB-1115LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1115LY-F(E)) | ELISA | Mouse Fab |
| HPAB-1116LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1116LY-F(E)) | ELISA | Mouse Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-114 | Afuco™ Anti-MUC16 ADCC Recombinant Antibody (Abagovomab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-H63 | Afuco™ Anti-MUC16 ADCC Recombinant Antibody (Sofituzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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