Anti-Human IL-1β (Interleukin 1 beta) Recombinant Antibody (47F11) (CAT#: TAB-231CT)

Recombinant monoclonal antibody to interleukin 1 beta. 47F11 is an antibody intended for the prophylaxis and treatment of inflammation.

Specific Inquiry
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  • Gene Expression
  • Datasheet
  • MSDS
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RNA Expression

Specifications

  • Immunogen
  • Recombinant human IL-1β
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • 47F11
  • Applications
  • Used for immunoassay techniques such as: Inhibition
  • Related Disease
  • Inflammation

Target

  • Alternative Names
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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