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Anti-NTRK2 Therapeutical Antibody (TAB-696CL)

Recombinant monoclonal antibody expressed in CHO binding to Human NTRK2. This is secreted protein that binds with high affinity to the extracellular domain of the tropomyosin-receptor kinase B (TrkB) receptor. It promote neuronal cell survival by activating the receptor and down-stream signaling proteins. We explored anti-TrkB antibodiess as a therapeutic strategy for Huntington's disease (HD).      

Specifications
Derivation
Mouse
Type
Antibody
Species Reactivity
Human
Related Disease
Huntington's Disease (HD)
Target
Alternative Names
NTRK2; neurotrophic tyrosine kinase, receptor, type 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; tropomyosin-related kinase B
Entrez Gene ID
4915
UniProt ID
Q16620

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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