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Recombinant Anti-TNFRSF8 Antibody (Fc glycosylation/Non fucosylated) (Gly-139LC-1)

This product is a non-fucosylated human monoclonal antibody. The antibody Defuc-5F11 with enhanced ADCC specficfically binds to human CD30 and can be potentially used in the treatment of lymphomas cancers.      

Glyco-engineering
Classification
Fc glycosylation/Non fucosylated
Glycosylation site
Asn297 in Fc region
Glycosylation Type
N-glycosylation
Activity
Enhanced ADCC
Specifications
Target
CD30 (Cluster of differentiation-30)
Host Animal
Human
Type
Human antibody
Specificity
Human
Antibody Isotype
IgG
Clone
Defuc-5F11
Expression Host
CHO DG44
Applications
ELISA
Target
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor
Related Disease
Lymphomas cancers
Entrez Gene ID
943
UniProt ID
A5D8T4

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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