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Anti-DSG3 antibody, clone PVA3 (DrMAB-172)

Recombinant Human Antibody binds selectively to Human DSG3.      

Specifications
Immunogen
Made by immortalizing IgG-expressing B cells from Pemphigus vulgaris (PV) patients.
Host
Human
Type
IgG
Specificity
This antibody specifically recognizes a conformational epitope in the EC3 domain of Human desmoglein-3 (DSG) and DSG-1. This antibody was isolated as a Human IgG1 from a patient with mucocutaneous pemphigus vulgaris and uses the VH3-15*01, D4-4*01, JH4*03, VL2-14*01 and JL1*01. This antibody does not have in vitro and in vivo pathogenic activity, as assessed in a keratinocyte dissociation assay.
Species Reactivity
Human
Clone
PVA3
Target
Alternative Names
DSG3; desmoglein 3; desmoglein 3 (pemphigus vulgaris antigen); desmoglein-3; CDHF6; pemphigus vulgaris antigen; cadherin family member 6; 130-kD pemphigus vulgaris antigen
Entrez Gene ID
1830
UniProt ID
P32926

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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