A*01:01/Human FLT3 ITD (YVDFREYEYY) MHC Pentamer (CAT#: MHC-YF438)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed FLT3 ITD-derived peptide of YVDFREYEYY sequence and A*01:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47539/1674_A6_32_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47539/1674_A6_32_selected.jpg
Figure 2 RNA cell line category: Group enriched (REH, THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000122025-FLT3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000122025-FLT3
Specifications
- Allele
- A*01:01
- Class
- Class I
- Antigen
- FLT3 ITD
- Antigen Species
- Human
- Peptide
- YVDFREYEYY
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
- Alternative Names
- Fms Related Tyrosine Kinase 3; Stem Cell Tyrosine Kinase 1; Fms-Like Tyrosine Kinase 3; FL Cytokine Receptor; CD135 Antigen; EC 2.7.10.1; CD135; FLK-2; STK1; FLK2;
- Gene ID
- 2322
- UniProt ID
- P36888
Downloads
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See other products for "FLT3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1630z | Mouse Anti-FLT3 Recombinant Antibody (clone 23F1) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| MOB-0606CT | Recombinant Mouse anti-Human FLT3 Monoclonal antibody (CW20B5) | FC, IP | |
| HPAB-0182CQ | Human Anti-FLT3 Recombinant Antibody (clone D4-3) | ELISA, Neut | Human IgG1, κ |
| HPAB-0183CQ | Human Anti-FLT3 Recombinant Antibody (clone NC7) | ELISA, Neut | Human IgG1, κ |
| VS3-XY714 | Mouse Anti-FLT3 Recombinant Antibody (clone 7B7C3) | ELISA, WB, IHC | Mouse IgG1 |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-291CL | Anti-Human FLT3 Recombinant Antibody (IMC-EB10) | WB, IHC, FC, Cyt, ELISA | Antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-010CQ | Anti-Human FLT3 Recombinant Antibody (BV10A4H2) | FC | |
| TAB-011CQ | Mouse Anti-FLT3 Recombinant Antibody (TAB-011CQ) | ELISA, FC | Mouse IgG1, κ |
| TAB-014CQ | Mouse Anti-FLT3 Recombinant Antibody (TAB-014CQ) | ELISA, FC | Mouse IgG1, κ |
| TAB-010CQ-S(P) | Anti-Human FLT3 Recombinant Antibody scFv Fragment (BV10A4H2) | ELISA, FC | |
| TAB-011CQ-S(P) | Mouse Anti-FLT3 Recombinant Antibody; scFv Fragment (TAB-011CQ-S(P)) | ELISA, FC | Mouse scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-012CQ | Human Anti-FLT3 Recombinant Antibody (TAB-012CQ) | ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
| TAB-013CQ | Human Anti-FLT3 Recombinant Antibody (TAB-013CQ) | ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
| TAB-012CQ-S(P) | Human Anti-FLT3 Recombinant Antibody; scFv Fragment (TAB-012CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-012CQ-F(E) | Human Anti-FLT3 Recombinant Antibody; Fab Fragment (TAB-012CQ-F(E)) | ELISA, FC | Chimeric (Mouse/Human) Fab |
| TAB-013CQ-F(E) | Human Anti-FLT3 Recombinant Antibody; Fab Fragment (TAB-013CQ-F(E)) | ELISA, FC | Chimeric (Mouse/Human) Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1323 | Hi-Affi™ Rabbit Anti-FLT3 Recombinant Antibody (clone DS1323AB) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0103-YC-S(P) | Human Anti-FLT3 Recombinant Antibody; scFv Fragment (HPAB-0103-YC-S(P)) | ELISA, Block, FC | Human scFv |
| HPAB-0182CQ-S(P) | Human Anti-FLT3 Recombinant Antibody (clone D4-3); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-0183CQ-S(P) | Human Anti-FLT3 Recombinant Antibody (clone NC7); scFv Fragment | ELISA, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0103-YC-F(E) | Human Anti-FLT3 Recombinant Antibody; Fab Fragment (HPAB-0103-YC-F(E)) | ELISA, Block, FC | Humanized Fab |
| HPAB-0182CQ-F(E) | Human Anti-FLT3 Recombinant Antibody (clone D4-3); Fab Fragment | ELISA, Neut | Human Fab |
| HPAB-0183CQ-F(E) | Human Anti-FLT3 Recombinant Antibody (clone NC7); Fab Fragment | ELISA, Neut | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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