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A*02:01/Human Hepatocyte growth factor receptor (YVDPVITSI) MHC Pentamer (CAT#: MHC-YF474)

MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed Hepatocyte growth factor receptor-derived peptide of YVDPVITSI sequence covering 673-681 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.


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Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55607/if_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/if_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18577/if_selected.jpg
Normal Tissue
Figure 4 Kidney
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_7_5.jpg
Figure 5 Testis
Figure 5 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5282/15802_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (A-431, CAPAN-2)
Figure 6 RNA cell line category: Cell line enhanced (A-431, CAPAN-2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105976-MET

Specifications

  • Allele
  • A*02:01
  • Class
  • Class I
  • Antigen
  • Hepatocyte growth factor receptor
  • Antigen Species
  • Human
  • Peptide
  • YVDPVITSI
  • Range
  • 673-681
  • Conjugate
  • Unlabeled, Biotin, R-PE, APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]
  • Alternative Names
  • MET Proto-Oncogene, Receptor Tyrosine Kinase; Hepatocyte Growth Factor Receptor; Tyrosine-Protein Kinase Met; Scatter Factor Receptor; Proto-Oncogene C-Met; HGF/SF Receptor; HGF Receptor; SF Receptor; EC 2.7.10.1;

Related Resources

  • Related Diseases

Downloads

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See other products for "MET"

Humanized Antibody

CAT Product Name Application Type
TAB-H24 Anti-Human MET Recombinant Antibody (Emibetuzumab) FuncS, IF, Neut, ELISA, FC, IP, WB IgG4 - kappa
TAB-521CL Anti-Human MET Recombinant Antibody (ABT-700) WB, FuncS Antibody
TAB-0881CLV-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (TAB-0881CLV-F(E)) ELISA, FuncS Humanized Fab
TAB-0883CLV-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (TAB-0883CLV-F(E)) ELISA, FuncS Humanized Fab
TAB-0884CLV-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (TAB-0884CLV-F(E)) ELISA, FuncS Humanized Fab

Immunotoxin

CAT Product Name Application Type
AGTO-G049E Anti-MET immunotoxin (Fab)-PE Cytotoxicity assay, Function study

Recombinant Antibody

CAT Product Name Application Type
PABL-271 Human Anti-MET Recombinant Antibody (clone 5D5) WB, Block, FuncS Human IgG
MOB-1226CT Recombinant Mouse anti-Human MET Monoclonal antibody (9G22) IHC-Fr, IHC-P
HPAB-0123-FY Camelid Anti-MET Recombinant Antibody (HPAB-0123-FY) ELISA Llama IgG1, λ
HPAB-1298LY Human Anti-MET Recombinant Antibody (HPAB-1298LY) ELISA, IP Human IgG2
HPAB-1299LY Human Anti-MET Recombinant Antibody (HPAB-1299LY) ELISA, IP Human IgG2

ADCC Enhanced Antibody

CAT Product Name Application Type
PABZ-155 Afuco™ Anti-MET ADCC Recombinant Antibody (Onartuzumab), ADCC Enhanced ELISA, Neut ADCC enhanced antibody
AFC-TAB-H24 Afuco™ Anti-MET ADCC Recombinant Antibody (Emibetuzumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

Chimeric Antibody

CAT Product Name Application Type
TAB-002MZ Anti-Human MET Recombinant Antibody (MvDN30) IHC, PET imaging Chimeric antibody (mouse/human)
TAB-002MZ-S(P) Anti-Human MET Recombinant Antibody scFv Fragment (MvDN30) IHC, PET imaging Chimeric antibody (mouse/human)
TAB-0880CLV Human Anti-MET Recombinant Antibody (TAB-0880CLV) ELISA, FuncS Chimeric (mouse/human) IgG1
TAB-0880CLV-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (TAB-0880CLV-F(E)) ELISA, FuncS Chimeric (mouse/human) Fab
TAB-0880CLV-S(P) Mouse Anti-MET Recombinant Antibody; scFv Fragment (TAB-0880CLV-S(P)) ELISA, FuncS Mouse scFv

Mouse Antibody

CAT Product Name Application Type
TAB-011MZ Mouse Anti-MET Recombinant Antibody (TAB-011MZ) ELISA, WB, FC Mouse IgG
TAB-012MZ Mouse Anti-MET Recombinant Antibody (TAB-012MZ) ELISA, WB, FC Mouse IgG
TAB-027MZ Mouse Anti-MET Recombinant Antibody (TAB-027MZ) WB, IP, IF Mouse lgG1
TAB-028MZ Mouse Anti-MET Recombinant Antibody (TAB-028MZ) IP Mouse lgG1
TAB-029MZ Mouse Anti-MET Recombinant Antibody (TAB-029MZ) IP, WB Mouse lgG1

Human Antibody

CAT Product Name Application Type
TAB-034MZ-S(P) Anti-Human MET Recombinant Antibody scFv Fragment (PGIA-1-A1) WB, ELISA Human antibody
TAB-035MZ-S(P) Anti-Human MET Recombinant Antibody scFv Fragment (PGIA-3-A9) WB, ELISA Human antibody
TAB-036MZ-S(P) Anti-Human MET Recombinant Antibody scFv Fragment (PGIA-3-A11) WB, ELISA Human antibody
TAB-037MZ-S(P) Anti-Human MET Recombinant Antibody scFv Fragment (PGIA-3-B2) WB, ELISA Human antibody
TAB-038MZ-S(P) Anti-Human MET Recombinant Antibody scFv Fragment (PGIA-4-A5) WB, ELISA Human antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1726CQ Recombinant Rabbit Anti-MET Antibody (CBL1008) Neut IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2216 Hi-Affi™ Recombinant Rabbit Anti-MET Monoclonal Antibody (DS2216AB) ICC/IF, IHC-P, WB IgG
MOR-4519 Hi-Affi™ Recombinant Rabbit Anti-MET Monoclonal Antibody (TH27DS) WB, IF, ICC IgG
MOR-4645 Hi-Affi™ Recombinant Rabbit Anti-MET Monoclonal Antibody (TH158DS) WB, IF, ICC, FC, ELISA IgG
MOR-4694 Hi-Affi™ Recombinant Rabbit Anti-MET Monoclonal Antibody (TH208DS) WB, ELISA IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-1298LY-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1298LY-F(E)) ELISA, IP Human Fab
HPAB-1299LY-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1299LY-F(E)) ELISA, IP Human Fab
HPAB-1300LY-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1300LY-F(E)) ELISA, IP Human Fab
HPAB-1301LY-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1301LY-F(E)) ELISA, IP Human Fab
HPAB-1302LY-F(E) Human Anti-MET Recombinant Antibody; Fab Fragment (HPAB-1302LY-F(E)) ELISA, IP Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-N0176-YC-S(P) Mouse Anti-MET Recombinant Antibody; scFv Fragment (HPAB-N0176-YC-S(P)) ELISA, FC Mouse scFv
HPAB-0117-WJ-S(P) Mouse Anti-MET Recombinant Antibody; scFv Fragment (HPAB-0117-WJ-S(P)) ELISA, WB Mouse scFv
HPAB-0394-YJ-S(P) Human Anti-MET Recombinant Antibody (clone S1); scFv Fragment ELISA, WB, IP, FC Human scFv
HPAB-0486-FY-S(P) Mouse Anti-MET Recombinant Antibody; scFv Fragment (HPAB-0486-FY-S(P)) Inhib Mouse scFv
HPAB-0487-FY-S(P) Human Anti-MET Recombinant Antibody; scFv Fragment (HPAB-0487-FY-S(P)) Inhib Human scFv

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