A*02:01/Human Papillomavirus type 16 Transforming protein E7 (YMLDLQPETT) MHC Pentamer (CAT#: MHC-YC186)
MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with HPV16-derived peptide of YMLDLQPETT sequence covering 11-20 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.
Specific Inquiry
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- Human Papillomavirus type 16 Transforming protein E7
- Antigen Species
- HPV16
- Peptide
- YMLDLQPETT
- Range
- 11-20
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- E7 plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
- Alternative Names
- HpV16gp2
- Gene ID
- 1489079
- UniProt ID
- P03129
Downloads
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See other products for "HPV16 E7"
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B047(A) | Recombinant Anti-HPV16 E7 Intrabody [(D-Arg)9] | ICC, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B047(G) | Recombinant Anti-HPV16 E7 Intrabody [+36 GFP] | ELISA, WB, ICC, FuncS | scFv-(+36GFP) |
| IAB-B047(T) | Recombinant Anti-HPV16 E7 Intrabody [Tat] | IF, FC, WB, FuncS | scFv-Tat |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-543LC | Anti-HPV16 E7 Recombinant Antibody (6C10) | ELISA | Mouse antibody |
| MRO-546LC | Anti-HPV16 E7 Recombinant Antibody | ELISA | Rabbit antibody |
| MRO-552LC | Anti-HPV16 E7 Recombinant Antibody (8E5) | ELISA | Mouse antibody |
| MRO-553LC | Anti-HPV16 E7 Recombinant Antibody (8C10) | ELISA | Mouse antibody |
| MRO-554LC | Anti-HPV16 E7 Recombinant Antibody (8G9) | ELISA | Mouse antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1877CQ | Recombinant Mouse Anti-HPV-16 E7 Antibody (0.N.332) | ELISA, FC, IF | Mouse antibody |
| MRO-1878CQ | Recombinant Mouse Anti-HPV-16 E7 Antibody (10F268) | ELISA, WB | Mouse antibody |
| MRO-1879CQ | Recombinant Mouse Anti-HPV-16 E7 Antibody (10F269) | ELISA, WB | Mouse antibody |
| MRO-1880CQ | Recombinant Mouse Anti-HPV-16 E7 Antibody (13B232) | ELISA, WB | Mouse antibody |
| MRO-1881CQ | Recombinant Mouse Anti-HPV-16 E7 Antibody (2C11) | IHC-P, WB, ELISA | Mouse antibody |
MHC Tetramer for Virology
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2328LY-F(E) | Rabbit Anti-HPV16 E7 Recombinant Antibody; Fab Fragment (HPAB-2328LY-F(E)) | ELISA, ICC | Rabbit Fab |
| FAMAB-0191WJ-F(E) | Mouse Anti-HPV16 E7 Recombinant Antibody (clone 69E2); Fab Fragment | ICC, IF, IHC, ELISA, WB, Neut | Mouse Fab |
| FAMAB-0192WJ-F(E) | Mouse Anti-HPV16 E7 Recombinant Antibody (clone 79A11); Fab Fragment | ICC, IF, IHC, ELISA, WB, Neut | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2328LY-S(P) | Rabbit Anti-HPV16 E7 Recombinant Antibody; scFv Fragment (HPAB-2328LY-S(P)) | ELISA, ICC | Rabbit scFv |
| FAMAB-0191WJ-S(P) | Mouse Anti-HPV16 E7 Recombinant Antibody (clone 69E2); scFv Fragment | ICC, IF, IHC, ELISA, WB, Neut | Mouse scFv |
| FAMAB-0192WJ-S(P) | Mouse Anti-HPV16 E7 Recombinant Antibody (clone 79A11); scFv Fragment | ICC, IF, IHC, ELISA, WB, Neut | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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