Mouse Anti-ABCB1 Recombinant Antibody (clone MRK16) (CAT#: FAMAB-1015CQ)
This product is a recombinant mouse antibody that recognizes ABCB1. The antibody was purified by affinity chromatography. It can be used in IP, FC, IF.
Specific Inquiry
FC
Figure 1 Biotinylation of cell surface proteins of HCT-15 cells and its effect on detection of P-gp level and function.
HCT-15 cells treated without (black trace) or with biotin (red trace) were subjected to staining by P-gp-specific antibodies MRK-16 followed by FITC-conjugated anti-mouse secondary antibody, to determine the cell surface level of P-gp.
Katayama, K., Kapoor, K., Ohnuma, S., Patel, A., Swaim, W., Ambudkar, I. S., & Ambudkar, S. V. (2015). Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway. Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 1853(10), 2361-2370.
Specifications
- Immunogen
- Drug resistant K-562 cells
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- P-glycoprotein
- Species Reactivity
- Human
- Clone
- MRK16
- Applications
- FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry.
Target
- Alternative Names
- ATP Binding Cassette Subfamily B Member 1; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1; Multidrug Resistance Protein 1; Colchicin Sensitivity; P-Glycoprotein 1; EC 3.6.3.44; MDR1; PGY1; ATP-Binding Cassette Sub-Family B Member 1; Doxorubicin Resistance
- Gene ID
- 5243
- UniProt ID
- P08183
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone MRK16"
See other products for "ABCB1"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-22-F(E) | Recombinant Anti-human ABCB1 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| MHH-22-F(E) | Recombinant Human Anti-human ABCB1 Antibody Fab Fragment | WB, FC, FuncS | Fab |
| PFBC-052 | Mouse Anti-ABCB1 Recombinant Antibody (clone C219); Fab Fragment | WB, Neut, IF, IHC, IHC-P, IP | Mouse IgG |
| PFBC-444 | Human Anti-ABCB1 Recombinant Antibody (clone UIC2); Fab Fragment | FC, Block, IP, IHC | Human Fab |
| HPAB-M0001-YC-F(E) | Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6); Fab Fragment | IHC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-22-S(P) | Recombinant Anti-human ABCB1 Antibody scFv Fragment | Neut, IF, FuncS | scFv |
| MHH-22-S(P) | Recombinant Human Anti-human ABCB1 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| PSBC-052 | Mouse Anti-ABCB1 Recombinant Antibody (clone C219); scFv Fragment | WB, Neut, IF, IHC, IHC-P, IP | Mouse scFv |
| PSBC-444 | Human Anti-ABCB1 Recombinant Antibody (clone UIC2); scFv Fragment | FC, Block, IP, IHC | Mouse scFv |
| HPAB-M0001-YC-S(P) | Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6); scFv Fragment | IHC | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-052 | Mouse Anti-ABCB1 Recombinant Antibody (clone C219) | WB, IF, IHC, FC, FuncS | Mouse IgG |
| PABC-444 | Human Anti-ABCB1 Recombinant Antibody (clone UIC2) | FuncS, FC, Block, IP, IHC | Human IgG1, κ |
| MRO-1138-CN | Rabbit Anti-ABCB1 Recombinant Antibody (clone CBACN-413) | WB, IHC | Rabbit IgG |
| HPAB-M0001-YC | Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6) | IHC | Mouse IgG |
| VS3-CJ488 | Rabbit Anti-ABCB1 Recombinant Antibody (VS3-CJ488) | WB, IHC | Rabbit IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-001CQ | Mouse Anti-ABCB1 Recombinant Antibody (clone UIC2) | FC, Block, IP, IHC | Mouse IgG2a, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0009 | Hi-Affi™ Rabbit Anti-ABCB1 Recombinant Antibody (clone DS9AB) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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