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Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6); scFv Fragment (CAT#: HPAB-M0001-YC-S(P))

Provided is a mouse anti-human MDR (MultiDrug Resistance)-1 monoclonal antibody. The cloning number of the hybridoma cell strain capable of secreting the MDR-1 monoclonal antibody is 6C6. The antibody can be used for scientific research or clinical immuno-histochemical detection of the MDR-1 expression.


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Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2199/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/74614/1893_J14_31_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/203_B4_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_B_9_5.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1716/4431_A_9_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (Hep G2, RH-30)
Figure 6 RNA cell line category: Cell line enhanced (Hep G2, RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000085563-ABCB1

Specifications

  • Immunogen
  • Prokaryotic expression of MDR-1
  • Host Species
  • Mouse
  • Type
  • Mouse scFv
  • Specificity
  • Human ABCB1
  • Species Reactivity
  • Human
  • Clone
  • 6C6
  • Applications
  • IHC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • ATP Binding Cassette Subfamily B Member 1; ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1; Multidrug Resistance Protein 1; Colchicin Sensitivity; P-Glycoprotein 1; EC 3.6.3.44; MDR1; PGY1; ATP-Binding Cassette Sub-Family B Member 1; Doxorubicin Resistance;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone 6C6"

See other products for "ABCB1"

Recombinant Antibody

CAT Product Name Application Type
MOB-22 Recombinant Anti-human ABCB1 Antibody WB, ELISA, IHC, FuncS IgG
MHH-22 Recombinant Human Anti-human ABCB1 Antibody FC, Neut, Funcs IgG
MOB-1496CT Mouse Anti-ABCB1 Recombinant Antibody (clone 5F4) FC, IF Mouse IgG2a
MRO-1138-CN Rabbit Anti-ABCB1 Recombinant Antibody (clone CBACN-413) WB, IHC Rabbit IgG
HPAB-0076-YJ Mouse Anti-ABCB1 Recombinant Antibody (clone MM4.17) IF, FC, IHC-P, ELISA Mouse IgG2a, κ

Fab Fragment Antibody

CAT Product Name Application Type
MOB-22-F(E) Recombinant Anti-human ABCB1 Antibody Fab Fragment FC, WB, FuncS Fab
MHH-22-F(E) Recombinant Human Anti-human ABCB1 Antibody Fab Fragment WB, FC, FuncS Fab
PFBC-052 Mouse Anti-ABCB1 Recombinant Antibody (clone C219); Fab Fragment WB, Neut, IF, IHC, IHC-P, IP Mouse IgG
PFBC-444 Human Anti-ABCB1 Recombinant Antibody (clone UIC2); Fab Fragment FC, Block, IP, IHC Human Fab
HPAB-M0001-YC-F(E) Mouse Anti-ABCB1 Recombinant Antibody (clone 6C6); Fab Fragment IHC Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-22-S(P) Recombinant Anti-human ABCB1 Antibody scFv Fragment Neut, IF, FuncS scFv
MHH-22-S(P) Recombinant Human Anti-human ABCB1 Antibody scFv Fragment FC, IP, FuncS scFv
PSBC-052 Mouse Anti-ABCB1 Recombinant Antibody (clone C219); scFv Fragment WB, Neut, IF, IHC, IHC-P, IP Mouse scFv
PSBC-444 Human Anti-ABCB1 Recombinant Antibody (clone UIC2); scFv Fragment FC, Block, IP, IHC Mouse scFv

Blocking Antibody

CAT Product Name Application Type
NEUT-001CQ Mouse Anti-ABCB1 Recombinant Antibody (clone UIC2) FC, Block, IP, IHC Mouse IgG2a, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0009 Hi-Affi™ Rabbit Anti-ABCB1 Recombinant Antibody (clone DS9AB) WB, IHC-P Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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