Human Anti-APS Recombinant Antibody (clone IS3) (CAT#: HPAB-1959-FY)

This product is a recombinant antibody that recognizes APS. The monoclonal antibody IS3 reacts with the epitope of APS.


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ELISA

Figure 1 Four monoclonal aCL bind to human β2GP1 alone.

Figure 1 Four monoclonal aCL bind to human β2GP1 alone.

Antibodies were used at 1 mg/ml (filled and open bars) or 10 mg/ml (slashed bars; denoted Ab 10X), except for CL15 and CL24 (which were used at 2 mg/ml and 20 mg/ml, respectively).

Zhu, M. , Olee, T. , Le, D. T. , Roubey, R. A. S. , Hahn, B. H. , & Woods, J. V. L. , et al. (1999). Characterization of igg monoclonal anti-cardiolipin/anti-beta2gp1 antibodies from two patients with antiphospholipid syndrome reveals three species of antibodies. British Journal of Haematology, 105(1), 102-109.

ELISA

Figure 2 Characterization of the serum cofactors for monoclonal aCL.

Figure 2 Characterization of the serum cofactors for monoclonal aCL.

All antibodies were used at 1 mg/ml, except for CL15 and CL24 which were used at 2 mg/ml.

Zhu, M. , Olee, T. , Le, D. T. , Roubey, R. A. S. , Hahn, B. H. , & Woods, J. V. L. , et al. (1999). Characterization of igg monoclonal anti-cardiolipin/anti-beta2gp1 antibodies from two patients with antiphospholipid syndrome reveals three species of antibodies. British Journal of Haematology, 105(1), 102-109.


Specifications

  • Host Species
  • Human
  • Derivation
  • Phage display library
  • Type
  • Human IgG
  • Specificity
  • Human APS
  • Species Reactivity
  • Human
  • Clone
  • IS3
  • Applications
  • ELISA
  • Related Disease
  • Autoimmune disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The APS antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.
    ELISA: 1 mg/ml.

Target

  • Alternative Names
  • Antiphospholipid syndrome; APS

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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