This product is a recombinant human antibody that recognizes CD4. The antibody was purified by affinity chromatography. It can be used in Neut, ELISA, FC.
Figure 1 Inhibition of HIV-1 Env-mediated fusion by sera from mice immunized with CD4-complexed HIV-1 Env.
era from mice immunized with autologous NIH 3T3 cells expressing HIV-1 Ba-L Env in complex or not with soluble CD4 were tested for inhibition of HIV-1 Env-mediated fusion using Sup-T1 cells chronically infected with HIV-1 Ba-L or IIIB as effector cells.
Burastero, S. E., Frigerio, B., Lopalco, L., Sironi, F., Breda, D., Longhi, R., ... & Lusso, P. (2011). Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4. PLoS One, 6(7), e22081.
Figure 2 Complement fixation by MAb DB81.
Flow cytometry analysis of PM-1 cells treated with complement (C) plus DB81. Cells were stained with propidium iodide as a marker for cell death. Numbers in panels indicate the percent of stained (complement lysed, dead) cells, which fell within the double arrow markers in the different experimental settings.
Burastero, S. E., Frigerio, B., Lopalco, L., Sironi, F., Breda, D., Longhi, R., ... & Lusso, P. (2011). Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4. PLoS One, 6(7), e22081.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-039 | Anti-Human CD4 Recombinant Antibody (Zanolimumab) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG1 - kappa |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-164 | Anti-Human CD4 Recombinant Antibody (Priliximab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 - kappa |
TAB-170LC | Human Anti-CD4 Recombinant Antibody (TAB-170LC) | ELISA, FC, ADCC, CDC, SPR | Chimeric antibody (rat/human) |
TAB-165LC-S(P) | Monkey Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-165LC-S(P)) | FC, SPR, ELISA | Monkey scFv |
TAB-167LC-S(P) | Anti-Human CD4 Recombinant Antibody scFv Fragment (cM-T412) | ELISA | Chimeric antibody (mouse/human) |
TAB-170LC-S(P) | Rat Anti-CD4 Recombinant Antibody; scFv Fragment (TAB-170LC-S(P)) | ELISA, SPR | Rat scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-146 | Anti-Human CD4 Recombinant Antibody (Ibalizumab) | FuncS, IF, Neut, ELISA, FC, IP, ICC | IgG4 - kappa |
TAB-161LC-F(E) | Anti-Human CD4 Recombinant Antibody Fab Fragment (gOKT4A-4) | ELISA | Humanized antibody |
TAB-168LC-F(E) | Anti-Human CD4 Recombinant Antibody Fab Fragment (TRX1) | ELISA | Humanized antibody |
TAB-171LC-F(E) | Human Anti-CD4 Recombinant Antibody; Fab Fragment (TAB-171LC-F(E)) | ELISA, SPR | Humanized Fab |
TAB-172LC-F(E) | Human Anti-CD4 Recombinant Antibody; Fab Fragment (TAB-172LC-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G078E | Anti-CD4 immunotoxin M-T151 (IgG)-PE | Cytotoxicity assay, Function study | |
AGTO-G078R | Anti-CD4 immunotoxin M-T151 (IgG)-RTA | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-033 | Human Anti-CD4 Recombinant Antibody (clone 17b); Fab Fragment | WB, ELISA, FuncS | Human Fab |
FAMAB-0054-YC-F(E) | Mouse Anti-CD4 Recombinant Antibody (clone M-T310); Fab Fragment | Neut | Mouse Fab |
FAMAB-0055-YC-F(E) | Mouse Anti-CD4 Recombinant Antibody (clone M-T404); Fab Fragment | Neut | Mouse Fab |
FAMAB-0056-YC-F(E) | Mouse Anti-CD4 Recombinant Antibody (clone M-T408); Fab Fragment | Neut | Mouse Fab |
FAMAB-0057-YC-F(E) | Mouse Anti-CD4 Recombinant Antibody (clone M-T151); Fab Fragment | Neut | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-160LC-F(E) | Anti-Human CD4 Recombinant Antibody Fab Fragment (OKT4A) | ELISA | |
TAB-166LC-F(E) | Anti-Human CD4 Recombinant Antibody Fab Fragment (M-T412) | ELISA | |
TAB-169LC-F(E) | Rat Anti-CD4 Recombinant Antibody; Fab Fragment (TAB-169LC-F(E)) | ELISA, SPR | Rat Fab |
TAB-173LC-F(E) | Anti-Human CD4 Recombinant Antibody Fab Fragment (IgA F425-Alg8) | ELISA | |
TAB-174LC-F(E) | Mouse Anti-CD4 Recombinant Antibody; Fab Fragment (TAB-174LC-F(E)) | ELISA, FC, IH | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-025LC | Recombinant Anti-Human CD4 Antibody (Fab glycosylation) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-0272MZ | Mouse Anti-CD4 Recombinant Antibody (clone 5C13) | IHC | Mouse IgG1 |
FAMAB-0048CQ | Mouse Anti-CD4 Recombinant Antibody (clone Leu3a) | ELISA, FC, Block, FuncS | Mouse IgG1, κ |
HPAB-0758-CN | Human Anti-CD4 Recombinant Antibody (clone Variant B) | ELISA, FC | Human IgG1 |
HPAB-0759-CN | Human Anti-CD4 Recombinant Antibody (clone Variant D) | ELISA, FC | Human IgG1 |
HPAB-0792-CN | Mouse Anti-CD4 Recombinant Antibody (clone B4) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-351CQ | Mouse Anti-CD4 Recombinant Antibody (clone 10C12) | ELISA, WB, IF, Block | Mouse IgG1 |
NEUT-352CQ | Mouse Anti-CD4 Recombinant Antibody (clone 13B8.2) | Block, ELISA, FC, IHC-Fr, WB | Mouse IgG1, κ |
NEUT-355CQ | Mouse Anti-CD4 Recombinant Antibody (clone RPA-T4) | FC, CyTOF, Block, IHC | Mouse IgG1, κ |
NEUT-357CQ | Rat Anti-CD4 Recombinant Antibody (clone MAB0810) | Block, Depletion, Stim | Rat IgG2b |
NEUT-358CQ | Rat Anti-CD4 Recombinant Antibody (clone RM4-5) | FC, CyTOF, Depletion, Block, IHC | Rat IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-353CQ | Mouse Anti-CD4 Recombinant Antibody (clone CBL976) | FC, Neut, IF, IHC | Mouse IgG1, κ |
NEUT-354CQ | Recombinant Mouse Anti-CD4 Antibody (CT-4) | Neut, FC, IHC, IHC-Fr, IHC-P, IP | IgG1, κ |
NEUT-356CQ | Mouse Anti-CD4 Recombinant Antibody (clone 3-4F4) | Neut, FC, IHC, IHC-Fr, IP, ICC | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0560 | Hi-Affi™ Rabbit Anti-CD4 Recombinant Antibody (clone DS560AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-039 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Zanolimumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
AFC-TAB-164 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Priliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-260 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Tregalizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-171 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Keliximab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-107 | Afuco™ Anti-CD4 ADCC Recombinant Antibody (Cedelizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2059LY-S(P) | Mouse Anti-CD4 Recombinant Antibody; scFv Fragment (HPAB-2059LY-S(P)) | FC | Mouse scfv |
HPAB-0557-WJ-S(P) | Human Anti-CD4 Recombinant Antibody (clone TRX1); scFv Fragment | ELISA | Human scFv |
HPAB-0558-WJ-S(P) | Human Anti-CD4 Recombinant Antibody (clone 6G5); scFv Fragment | ELISA | Human scFv |
HPAB-0957WJ-S(P) | Human Anti-CD4 Recombinant Antibody (clone 4-91); scFv Fragment | ELISA | Human scFv |
HPAB-2112-FY-S(P) | Mouse Anti-CD4 Recombinant Antibody (clone MT15.1); scFv Fragment | Inhib | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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