Mouse Anti-CDH1 Recombinant Antibody (clone 66E8) (CAT#: PABJ-0035)
This product is a mouse antibody that recognizes human CDH1. CDH1 is involved in mechanisms regulating intercellular adhesion, mobility, and proliferation of epithelial cells. Diseases associated with CDH1 include diffuse gastric and lobular breast cancer syndromes and palpebral labial syndrome 1. This antibody has an activating effect on CDH1 and binds to the EC1-2 epitope of CDH1.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28364/672_E7_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28364/672_E7_2_selected.jpg
Figure 2 ParaThyroid gland
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4812/158154_A_3_8_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4812/158154_A_3_8_val_selected.jpg
Figure 3 Colon
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_9_3.jpg
(Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Microvilli Staining: High Intensity: Strong Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_9_3.jpg
Figure 4 Liver
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_4.jpg
(Cholangiocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_4.jpg
Figure 5 Kidney
(Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_5.jpg
(Bowman's capsule Staining: Medium Intensity: Moderate Quantity:>75% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_7_5.jpg
Figure 1 Urinary bladder
(Urothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_5_5.jpg
(Urothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72856/157200_A_5_5.jpg
Figure 1 RNA cell line category: Cell line enhanced (BEWO, CACO-2, CAPAN-2, HaCaT, hTCEpi, MCF7, OE19, RT4, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000039068-CDH1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000039068-CDH1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human CDH1
- Species Reactivity
- Human
- Clone
- 66E8
- Applications
- ELISA
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- CDH1; cadherin 1; UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324; E-cadherin; cadherin-1; CAM 120/80; E-cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, type 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial; cell-CAM 120/80; epididymis secretory sperm binding protein; epithelial cadherin; uvomorulin
- Gene ID
- 999
- UniProt ID
- P12830
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 66E8"
See other products for "CDH1"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1411CL | Anti-Human CDH1 Recombinant Antibody (hSC10.17) | Cyt, FuncS, Inhib | Humanized antibody |
| TAB-1411CL-S(P) | Anti-Human CDH1 Recombinant Antibody scFv Fragment (hSC10.17) | ELISA | Humanized antibody |
| TAB-1411CL-F(E) | Anti-Human CDH1 Recombinant Antibody Fab Fragment (hSC10.17) | ELISA | Humanized antibody |
Mouse Antibody
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0111MZ | Chicken Anti-CDH1 Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-440CQ | Rat Anti-CDH1 Recombinant Antibody (clone DECMA-1) | FC, FuncS, Neut, WB, IF, IP | Rat IgG1, κ |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-441CQ | Rat Anti-Cdh1 Recombinant Antibody (clone ECCD-1) | IHC-Fr, Block, ICC, IF, WB | Rat IgG1 |
| NEUT-442CQ | Mouse Anti-CDH1 Recombinant Antibody (VMC173) | ELISA, FC, ICC, IF, IHC, IP, WB, IHC-P, IHC-Fr, Block | Mouse IgG1 |
| NEUT-443CQ | Mouse Anti-CDH1 Recombinant Antibody (VMC174) | ELISA, IP, WB, ICC, Block, FC, IHC-P | Mouse IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0611 | Hi-Affi™ Rabbit Anti-CDH1 Recombinant Antibody (clone DS611AB) | ICC, IF, IHC-P, IHC-P, IP, WB | Rabbit IgG |
| MOR-4569 | Hi-Affi™ Rabbit Anti-CDH1 Recombinant Antibody (clone TH81DS) | WB, IF, ICC, FC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1162-CN | Rabbit Anti-CDH1 Recombinant Antibody (clone CBACN-423) | WB, IF, IHC, IP, FC | Rabbit IgG |
| ZG-0269J | Mouse Anti-CDH1 Recombinant Antibody (ZG-0269J) | WB, ELISA | Mouse IgG |
| ZG-0270J | Mouse Anti-CDH1 Recombinant Antibody (ZG-0270J) | WB | Mouse IgG |
| ZG-1051F | Mouse Anti-CDH1 Recombinant Antibody (clone MB2) | FC, ICC, IHC-Fr, WB | Mouse IgG2b |
| ZG-1104F | Mouse Anti-CDH1 Recombinant Antibody (clone SEC21) | IB | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0464-WJ-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.6); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0465-WJ-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.15); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0466-WJ-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.17); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-0467-WJ-F(E) | Human Anti-CDH1 Recombinant Antibody (clone hSC10.17); Fab Fragment | ELISA, FC | Humanized Fab |
| PABJ-0035-F(E) | Mouse Anti-CDH1 Recombinant Antibody (clone 66E8); Fab fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0464-WJ-S(P) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.6); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0465-WJ-S(P) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.15); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0466-WJ-S(P) | Mouse Anti-CDH1 Recombinant Antibody (clone SC10.17); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0467-WJ-S(P) | Human Anti-CDH1 Recombinant Antibody (clone hSC10.17); scFv Fragment | ELISA, FC | Humanized scFv |
| PABJ-0035-S(P) | Mouse Anti-CDH1 Recombinant Antibody (clone 66E8); scFv Fragment | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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