Human Anti-CR1 Recombinant Antibody (clone E11) (CAT#: FAMAB-1103CQ)

This product is a recombinant human antibody that recognizes CR1. The antibody was purified by affinity chromatography. It can be used in WB, ELISA, IF.


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IF

Figure 1 CR1 expressed by CHO cells is recognized by anti-CR1 antibodies.

Figure 1 CR1 expressed by CHO cells is recognized by anti-CR1 antibodies.

CR1 immunofluorescence staining using mouse mAbs E11 on fixed CHO cells. Scale bar: 50 μm.

Fonseca, M. I., Chu, S., Pierce, A. L., Brubaker, W. D., Hauhart, R. E., Mastroeni, D., ... & Tenner, A. J. (2016). Analysis of the putative role of CR1 in Alzheimer’s disease: genetic association, expression and function. PloS one, 11(2), e0149792.

IP

Figure 2 Immunoprecipitation of CR1 with mAb E11.

Figure 2 Immunoprecipitation of CR1 with mAb E11.

Immunoprecipitates of E11 (4 μg) (lanes 3, 5, 7) or IgG1 (4 μg) (lanes 2, 4, 6) with sCR1 (2 μg) (lanes 2,3), RBC from a MCI subject (TT/GG) (50 μg protein, lane 4, 5) or brain extracts from cognitively intact subject (AT/AG) (250 μg, lane 6, 7). sCR1 isloaded at 1 ng (lane 1).

Fonseca, M. I., Chu, S., Pierce, A. L., Brubaker, W. D., Hauhart, R. E., Mastroeni, D., ... & Tenner, A. J. (2016). Analysis of the putative role of CR1 in Alzheimer’s disease: genetic association, expression and function. PloS one, 11(2), e0149792.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1
  • Species Reactivity
  • Human
  • Clone
  • E11
  • Applications
  • IF, IP

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Immunoprecipitation and Immunofluorescence.

Target

  • Alternative Names
  • Complement C3b/C4b Receptor 1 (Knops Blood Group); Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Complement Component 3b/4b Receptor 1 (Knops Blood Group)

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone E11"

See other products for "CR1"

Blocking Antibody

CAT Product Name Application Type
NEUT-496CQ Mouse Anti-CR1 Recombinant Antibody (clone J3D3) Block, ELISA, FC, IHC-Fr, IHC-P Mouse IgG1, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0794 Hi-Affi™ Rabbit Anti-CR1 Recombinant Antibody (clone DS794AB) WB, IHC Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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