Human Anti-DENV E Recombinant Antibody (clone DVC21) (CAT#: FAMAB-1690CQ)
This product is a recombinant human antibody that recognizes DENV E. The antibody was purified by affinity chromatography. It can be used in Neut, WB, ELISA, FC.
Specific Inquiry
Figure 1 Human monoclonal antibodies to dengue virus envelope increased viral production in primary human monocytes.
The assay set up using PBMC from a dengue-naïve subject, except that serial dilutions of monoclonal antibodies were used. The changes in infected cell percentage (a and c) and total virus production (b and d) in the presence of DIII-specific antibodies (DVC21.8 and DVC1.6) (a and b) and non-DIII antibodies (DVC23.13 and DVC35.3) (c and d) were presented. Each graph represents the results of one experiment.
Kou, Z., Lim, J. Y., Beltramello, M., Quinn, M., Chen, H., Liu, S. N., ... & Jin, X. (2011). Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes. Virology, 410(1), 240-247.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- DENV envelope protein domain III
- Species Reactivity
- DENV
- Clone
- DVC21
- Applications
- Neut, WB, ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- DENV E; Envelope proteins; E proteins
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone DVC21"
See other products for "DENV E"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-111 | Human Anti-DENV E Recombinant Antibody (clone DV10) | ELISA, NTRL | Human IgG |
| HPAB-S0024-YC | Mouse Anti-DENV E Recombinant Antibody (clone 2H12) | ELISA, Neut, FuncS | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0024-YC-F(E) | Mouse Anti-DENV E Recombinant Antibody (clone 2H12); Fab Fragment | ELISA, Neut, FuncS | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0024-YC-S(P) | Mouse Anti-DENV E Recombinant Antibody (clone 2H12); scFv Fragment | ELISA, Neut, FuncS | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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