Human Anti-FZD5 Recombinant Antibody (clone F2.I); scFv Fragment (CAT#: PABJ-0145-S(P))
This product is a Human antibody scFv fragment that recognizes Human FZD5. F2.I bound FZD1, -2, -4, -5, -7, and -8 on the cell surface, but did not bind FZD3, -6, -9, or -10. F2.I showed cross-reactivity to mouse FZD4 and FZD5.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human caudate
(Immunohistochemical staining of human caudate shows moderate positivity in neurons.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/ihc_selected.jpg
(Immunohistochemical staining of human caudate shows moderate positivity in neurons.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_B_7_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_B_7_5.jpg
Figure 3 Pancreas
(Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_2_3.jpg
(Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_2_3.jpg
Figure 4 Testis
(Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_6_6.jpg
(Elongated or late spermatids Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52361/127650_A_6_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (BEWO, CACO-2, Hep G2, NTERA-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163251-FZD5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000163251-FZD5
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human FZD5
- Species Reactivity
- Human
- Clone
- F2.I
- Applications
- ELISA, Inhib, FuncS
Product Property
- Purification
- Purified
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Inhibition, Functional Assay.
Target
- Alternative Names
- HFZ5; C2orf31; frizzled-5; Wnt receptor; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; fz-5; fzE5; seven-transmembrane receptor frizzled-5
- Gene ID
- 7855
- UniProt ID
- Q13467
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0749CT | Recombinant Mouse anti-Human FZD5 Monoclonal antibody (EML2242) | WB | |
| MRO-1876-CN | Rabbit Anti-FZD5 Polyclonal Antibody (MRO-1876-CN) | WB | Rabbit IgG |
| PABJ-0145 | Human Anti-FZD5 Recombinant Antibody (clone F2.I) | ELISA, Inhib, FuncS | Human IgG |
| VS3-QX453 | Mouse Anti-FZD5 Recombinant Antibody (clone 2D12) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABJ-0145-F(E) | Human Anti-FZD5 Recombinant Antibody (clone F2.I); Fab fragment | ELISA, Inhib, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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