Recombinant monoclonal antibody specially binds to HCV core. 2G3 is a mouse monoclonal antibody that can be potentially used in the treament of pateints with HCV infection.
Figure 1 Immunoprecipitation of HCV core protein from transformed REF cells.
Cells cotransfected with HCV core gene- and H-ras (A)- or c-myc (B)- transformed REF cells were labeled with [35S]methionine-cysteine.
Ray, R. B., Lagging, L. M., Meyer, K., & Ray, R. (1996). Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. Journal of Virology, 70(7), 4438-4443.
Figure 2 Indirect immunofluorescence using transformed REF cells.
Cells cotransfected with HCV core and c-myc genes and cells recovered from tumors generated by inoculation of HCV core gene.
Ray, R. B., Lagging, L. M., Meyer, K., & Ray, R. (1996). Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. Journal of Virology, 70(7), 4438-4443.
Figure 3 Comparison of the growth rates of REF cells transformed by cotransfection with HCV core and c-myc or H-ras genes.
All results are representative of at least four independent experiments.
Ray, R. B., Lagging, L. M., Meyer, K., & Ray, R. (1996). Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. Journal of Virology, 70(7), 4438-4443.
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CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-943 | Recombinant Human Anti-HCV Core Protein Antibody scFv Fragment | ELISA, PP, WB, IF, Inhib | scFv |
FAMAB-0300JF-S(P) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone DA3); scFv Fragment | IB, IP, ELISA, FuncS | Mouse scFv |
FAMAB-0301JF-S(P) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone AA10); scFv Fragment | IB, IP, ELISA, FuncS | Mouse scFv |
FAMAB-0302JF-S(P) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone 2G3); scFv Fragment | IB, IP, ELISA, FuncS | Mouse scFv |
FAMAB-0357JF-S(P) | Human Anti-HCV Core Protein Recombinant Antibody (clone 4C2); scFv Fragment | ELISA, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-019CT | Human Anti-HCV Core Protein Recombinant Antibody (TAB-019CT) | WB | Human IgG1 |
TAB-019CT-S(P) | Human Anti-HCV Core Protein Recombinant Antibody; scFv Fragment (TAB-019CT-S(P)) | WB | Human scFv |
TAB-019CT-F(E) | Human Anti-HCV Core Protein Recombinant Antibody; Fab Fragment (TAB-019CT-F(E)) | WB | Human Fab |
MRO-500LC-S(P) | Anti-HCV core protein Recombinant Antibody scFv Fragment (HCVHU.OT2) | ELISA | Human antibody |
MRO-500LC-F(E) | Anti-HCV core protein Recombinant Antibody Fab Fragment (HCVHU.OT2) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-655CQ | Recombinant Mouse Anti-HCV Core protein Antibody (H6-29) | WB, IF, IHC-Fr | Mouse antibody |
MRO-656CQ | Recombinant Mouse Anti-HCV Core protein Antibody (1851) | ELISA, IF, WB | Mouse antibody |
MRO-657CQ | Recombinant Mouse Anti-HCV Core protein Antibody (1868) | ELISA, IF, WB | Mouse antibody |
MRO-659CQ | Recombinant Mouse Anti-HCV Core protein Antibody (11-B3) | ELISA, IF, IHC-Fr, WB | Mouse antibody |
MRO-660CQ | Recombinant Mouse Anti-HCV Core protein Antibody (1E5) | ELISA, IP | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-481LC | Anti-HCV core protein Recombinant Antibody (1F2) | ELISA | Chimpanzee antibody |
MRO-481LC-S(P) | Anti-HCV core protein Recombinant Antibody scFv Fragment (1F2) | ELISA | Chimpanzee antibody |
MRO-481LC-F(E) | Anti-HCV core protein Recombinant Antibody Fab Fragment (1F2) | ELISA | Chimpanzee antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0365 | APC-E*01:0303/HCV Core (YLLPRRGPRL) MHC Tetramer | FCM | |
MHC-CN0366 | PE-E*01:0303/HCV Core (YLLPRRGPRL) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0298JF-F(E) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone CA7); Fab Fragment | IB, IP, ELISA, FuncS | Mouse Fab |
FAMAB-0299JF-F(E) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone 2H9); Fab Fragment | IB, IP, ELISA, FuncS | Mouse Fab |
FAMAB-0300JF-F(E) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone DA3); Fab Fragment | IB, IP, ELISA, FuncS | Mouse Fab |
FAMAB-0301JF-F(E) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone AA10); Fab Fragment | IB, IP, ELISA, FuncS | Mouse Fab |
FAMAB-0302JF-F(E) | Mouse Anti-HCV Core Protein Recombinant Antibody (clone 2G3); Fab Fragment | IB, IP, ELISA, FuncS | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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