Recombinant human antibody to gp120. This antibody can bind to several complementary regions of gp120 and synergistically neutralized a wide range of HIV subtypes.
Figure 1 Effect of sCD4 over binding of MAbs isolated from patient KTS376 to monomeric SF2gp120.
Reactivity to gp120 was examined for 39D5 MAb alone (gray diamond) or in the presence of sCD4 (black square) by capture ELISA assay.
Valdez, K. P. R., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., & Matsushita, S. (2015). Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains. Virology, 475, 187-203.
Figure 2 Binding of MAbs from patient KTS376 to Env expressed on the surface of cells.
Reactivity to PM1/CCR5 cells chronically infected with HIV-1JR-FL was analyzed using flow cytometer.
Valdez, K. P. R., Kuwata, T., Maruta, Y., Tanaka, K., Alam, M., Yoshimura, K., & Matsushita, S. (2015). Complementary and synergistic activities of anti-V3, CD4bs and CD4i antibodies derived from a single individual can cover a wide range of HIV-1 strains. Virology, 475, 187-203.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-165 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone GL-VRC01); scFv Fragment | Neut | Human scFv |
PSBZ-209 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 19.3H-L3); scFv Fragment | Neut | Human scFv |
PSBZ-210 | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 19.3H-L1); scFv Fragment | Neut | Human scFv |
MRO-3081CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone DH276); Fab Fragment | Neut | Human Fab |
MRO-3082CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone DH374); Fab Fragment | Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91C2) | ELISA | Single domain antibody |
MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91F10) | ELISA | Single domain antibody |
MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91E1) | ELISA | Single domain antibody |
MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91B5) | ELISA | Single domain antibody |
MRO-032LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91H9) | ELISA | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-041LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (D59/A2) | ELISA | Mouse antibody |
MRO-042LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (F58/H3) | ELISA | Mouse antibody |
MRO-043LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P1/D12) | ELISA | Mouse antibody |
MRO-044LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P4/D10) | ELISA | Mouse antibody |
MRO-045LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (A47/B1) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0178CQ-S(P) | Mouse Anti-HIV-1 gp120 Recombinant Antibody (clone C beta 1); scFv Fragment | WB, Neut | Mouse scFv |
MRO-3146CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone NIH45-46G54Y (45-46Y)); scFv Fragment | Neut | Human scFv |
MRO-3147CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone D02-20); scFv Fragment | ELISA, FC | Human scFv |
MRO-3527CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1108); scFv Fragment | Neut | Human scFv |
MRO-3528CQ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGT133); scFv Fragment | ELISA, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-3489CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 8ANC57) | Neut | Human IgG |
MRO-3490CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGDM11) | ELISA, Neut | Human IgG |
MRO-3491CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGDM12) | ELISA, Neut | Human IgG |
MRO-3492CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGDM13) | ELISA, Neut | Human IgG |
MRO-3493CQ | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 1125H (1125h)) | Neut | Human IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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