Human Anti-HIV-1 gp120 Recombinant Antibody (clone S20) (CAT#: HPAB-0201CQ)

This product is a recombinant human antibody that recognizes HIV-1 gp120. This antibody was capable of binding to protein gp120 of HIV-1.


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  • Purity:
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  • Published Data
  • Datasheet
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  • COA
ELISA

Figure 1 ELISA of binding properties of IgG Fab S19, S20 and S8 to recombinant gp120 III-B and other antigens.

Figure 1 ELISA of binding properties of IgG Fab S19, S20 and S8 to recombinant gp120 III-B and other antigens.

Torán, J. L., Kremer, L., Sánchez‐Pulido, L., de Alborán, I. M., del Real, G., Llorente, M.,... & Martínez‐A, C. (1999). Molecular analysis of HIV‐1 gp120 antibody response using isotype IgM and IgG phage display libraries from a long‐term non‐progressor HIV‐1‐infected individual. European journal of immunology, 29(9), 2666-2675.

FuncS

Figure 2 Shows binding properties of LTNP donor serum and anti-gp120 Fab.

Figure 2 Shows binding properties of LTNP donor serum and anti-gp120 Fab.

Gp120 and BSA binding of donor-derived polyreactive IgM Fab (M025) and high affinity IgG Fabs S8, S19 and S20.

ELISA

Figure 3 Shows gp120 binding by Fab S8 and S20 HCDR3 mutants.

Figure 3 Shows gp120 binding by Fab S8 and S20 HCDR3 mutants.

Shows gp120 binding by Fab S8 and S20 HCDR3 mutants Arg95 from S20 HCDR3 was replaced by the amino acids indicated in single letter code. Binding to gp120 and BSA by these Fab mutants, as well as by the unmutated forms and the related polyreactive Fab M025, was then tested in ELISA.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • HIV-1 gp120
  • Species Reactivity
  • HIV-1
  • Clone
  • S20
  • Applications
  • ELISA, Neut, FuncS
  • Related Disease
  • AIDS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Functional Assay. Please see the Published Data for further information.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone S20"

See other products for "HIV-1 gp120"

Single-domain Antibody

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) ELISA, WB, Neut Chimeric antibody (mouse/human)
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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