Mouse Anti-HSPD1 Recombinant Antibody (clone II-13) (CAT#: FAMAB-0119JF)

Recombinant monoclonal antibody specially binds to HSP60. This mouse anti-HSP60 antibody II-13 could be potentially used in the prevention or retardation of atherosclerosis via inhibition of autoimmune reactions.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FuncS

Figure 1 Comparison of protein expression of Hsp70, SCUBE3, and CXCL14 chemotactic factor in osteosarcoma cells and in normal osteoblasts.

Figure 1 Comparison of protein expression of Hsp70, SCUBE3, and CXCL14 chemotactic factor in osteosarcoma cells and in normal osteoblasts.

These results are representative of three independent experiments.

Liang, W., Yang, C., Peng, J., Qian, Y., & Wang, Z. (2015). The expression of HSPD1, SCUBE3, CXCL14 and its relations with the prognosis in osteosarcoma. Cell biochemistry and biophysics, 73(3), 763-768.

IHC

Figure 2 Representative results of immunohistochemistry of HSPD1-colon cancer.

Figure 2 Representative results of immunohistochemistry of HSPD1-colon cancer.

Main image, ×100.

Li, G., Li, M., Liang, X., Xiao, Z., Zhang, P., Shao, M., ... & Chen, Z. (2017). Identifying DCN and HSPD1 as potential biomarkers in colon cancer using 2D-LC-MS/MS combined with iTRAQ technology. Journal of Cancer, 8(3), 479.

WB

Figure 3 Expressional levels of DCN and HSPD1 in non-neoplastic colonic mucosa (NNCM) (N) and colon cancer (C).

Figure 3 Expressional levels of DCN and HSPD1 in non-neoplastic colonic mucosa (NNCM) (N) and colon cancer (C).

Representative results of Western blotting analysis of DCN and HSPD1 in NNCM (N) and colon cancer (C).

Li, G., Li, M., Liang, X., Xiao, Z., Zhang, P., Shao, M., ... & Chen, Z. (2017). Identifying DCN and HSPD1 as potential biomarkers in colon cancer using 2D-LC-MS/MS combined with iTRAQ technology. Journal of Cancer, 8(3), 479.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG2a
  • Specificity
  • Human HSP60
  • Species Reactivity
  • Human
  • Clone
  • II-13
  • Applications
  • WB, IHC, FuncS
  • Related Disease
  • Atherosclerosis

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HSPD1 antibody has been reported in applications of Western Blot, Immunohistochemistry, Functional Assay.

Target

  • Alternative Names
  • HSPD1; heat shock 60kDa protein 1 (chaperonin); HLD4; CPN60; GROEL; HSP60; HSP65; SPG13

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone II-13"

See other products for "HSPD1"

Humanized Antibody

CAT Product Name Application Type
TAB-110CT Anti-Human HSP60 Recombinant Antibody (prozumab) Inhibit, ELISA Humanized antibody
TAB-110CT-S(P) Anti-Human HSP60 Recombinant Antibody scFv Fragment (prozumab) Inhibit, ELISA Humanized antibody
TAB-110CT-F(E) Anti-Human HSP60 Recombinant Antibody Fab Fragment (prozumab) Inhibit, ELISA Humanized antibody

Mouse Antibody

CAT Product Name Application Type
MRO-018CT Recombinant Mouse Anti-HSP60 Antibody WB, IHC, FC

Blocking Antibody

CAT Product Name Application Type
NEUT-920CQ Mouse Anti-HSPD1 Recombinant Antibody (clone 4B9/89) Block, ELISA, ICC, IF, IHC, IHC-P, IP, WB Mouse IgG2a

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1704 Rabbit Anti-HSPD1 Recombinant Antibody (clone DS1704AB) IHC-P, WB Rabbit IgG
MOR-0077-FY Rabbit Anti-HSPD1 Recombinant Antibody (clone AFY0048) ICC, IHC-P, WB Rabbit IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC2077 PE-A*02:01/Human HSPD1 (KLSDGVAVL) MHC Tetramer FCM

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-1428LC Mouse Anti-HSPD1 Recombinant Antibody (clone 9C9) ELISA Mouse IgG1

MHC Tetramer for Other Applications

CAT Product Name Application Type
MHC-YF309 Qa-1b/Human Hsp60 (GMKFDRGYI) MHC Monomer MHC Multimer

scFv Fragment Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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