Human Anti-Il21r Recombinant Antibody (clone 18A5) (CAT#: HPAB-0668-CN)
This is a monoclonal antibody which specifically binds to the human interleukin-21 receptor (IL-21R). This mAb can act as the antagonist of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. This product has been detected by Flow cytometry and Immunohistochemistry.
Specific Inquiry
FC
Figure 1 IL-21R expression was determined by flow cytometry on peripheral blood mononuclear cells.
The percentage of IL-21R+ cells was assayed in the CD4+ lymphocytes.
Van Der Fits, L., Out-Luiting, J. J., Van Leeuwen, M. A., Samsom, J. N., Willemze, R., Tensen, C. P., & Vermeer, M. H. (2012). Autocrine IL-21 stimulation is involved in the maintenance of constitutive STAT3 activation in Sezary syndrome. Journal of investigative dermatology, 132(2), 440-447.
IHC
Figure 2 IL-21-specific receptor (IL-21R) expression in Sézary syndrome (SS) cells in skin biopsies.
Representative examples are shown.
Van Der Fits, L., Out-Luiting, J. J., Van Leeuwen, M. A., Samsom, J. N., Willemze, R., Tensen, C. P., & Vermeer, M. H. (2012). Autocrine IL-21 stimulation is involved in the maintenance of constitutive STAT3 activation in Sezary syndrome. Journal of investigative dermatology, 132(2), 440-447.
Specifications
- Host Species
- Human
- Derivation
- scFv phage display library
- Type
- Human IgG1
- Specificity
- Human Il21r
- Species Reactivity
- Human, Mouse
- Clone
- 18A5
- Applications
- FC, IHC
- Related Disease
- Inflammatory disorders, autoimmune diseases, allergies, transplant rejection, hyperproliferative disorders of the blood, other immune system disorders
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IL21R antibody has been reported in applications of Immunohistochemistry, Flow Cytometry.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 18A5"
See other products for "IL21R"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1347z | Mouse Anti-IL21R Recombinant Antibody (clone 44B3) | WB, IP, IF, ELISA | Mouse IgG2a, κ |
| HPAB-0669-CN | Human Anti-IL21R Recombinant Antibody (clone ABS) | ELISA, FC, Neut | Human IgG |
| FAMAB-1203CQ | Human Anti-IL21R Recombinant Antibody (clone ATR-107) | Inhib, FC, WB | Human IgG1 |
| VS3-FY279 | Recombinant Mouse Anti-IL21R Antibody (clone 1C3B12) | ELISA, FC | Mouse IgG1 |
| VS3-FY280 | Recombinant Mouse Anti-IL21R Antibody (clone 1C3G9) | ELISA, ICC, FC | Mouse IgG1 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-583LC | Rat Anti-IL21R Recombinant Antibody (TAB-583LC) | ELISA, WB | Rat IgG |
| TAB-584LC | Rat Anti-IL21R Recombinant Antibody (TAB-584LC) | ELISA, WB | Rat IgG |
| TAB-583LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-583LC-S(P)) | ELISA, WB | Rat scFv |
| TAB-584LC-S(P) | Rat Anti-IL21R Recombinant Antibody; scFv Fragment (TAB-584LC-S(P)) | ELISA, WB | Rat scFv |
| TAB-583LC-F(E) | Rat Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-583LC-F(E)) | ELISA, WB | Rat Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-585LC-F(E) | Human Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-585LC-F(E)) | ELISA, FC | Human Fab |
| TAB-586LC-F(E) | Human Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-586LC-F(E)) | ELISA, FC | Human Fab |
| TAB-587LC-F(E) | Human Anti-IL21R Recombinant Antibody; Fab Fragment (TAB-587LC-F(E)) | ELISA, FC | Human Fab |
| TAB-588LC-F(E) | Anti-human IL21R Fab Fragment (MUF) | ELISA, FC | Human antibody |
| TAB-589LC-F(E) | Anti-human IL21R Fab Fragment (MU11) | ELISA, FC | Human antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1327CQ | Rat Anti-Il21r Recombinant Antibody (VMC196) | Block | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4261 | Rabbit Anti-IL21R Recombinant Antibody (clone SI341DS) | ELISA | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0668-CN-S(P) | Human Anti-IL21R Recombinant Antibody (clone 18A5); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-0669-CN-S(P) | Human Anti-IL21R Recombinant Antibody (clone ABS); scFv Fragment | ELISA, FC, Neut | Human scFv |
| HPAB-0247CQ-S(P) | Human Anti-IL21R Recombinant Antibody (clone 19F5); scFv Fragment | ELISA, FC, Inhib | Human scFv |
| HPAB-AP685-YC-S(P) | Human Anti-IL21R Recombinant Antibody (clone C2); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0668-CN-F(E) | Human Anti-IL21R Recombinant Antibody (clone 18A5); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-0669-CN-F(E) | Human Anti-IL21R Recombinant Antibody (clone ABS); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-0247CQ-F(E) | Human Anti-IL21R Recombinant Antibody (clone 19F5); Fab Fragment | ELISA, FC, Inhib | Human Fab |
| HPAB-AP685-YC-F(E) | Human Anti-IL21R Recombinant Antibody (clone C2); Fab Fragment | ELISA | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0668-CN. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.