Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10) (CAT#: FAMAB-0365JF)
Recombinant monoclonal antibody specially binds to MFGE8 protein-bound 4-oxo-2-nonenal (ONE). 3D10 is a mouse monoclonal antibody that can play a critical role in removing multiple damage-associated molecules, including oxidation-specific epitopes and late apoptotic/necrotic cells thyroid autoimmunity.
Specific Inquiry
IHC
Figure 1 Inhibition ofthe MFG-E8 receptorreduces LPS-induced inflammatory neuronal loss.
Data are means ± SEM.
Miksa, M., Amin, D., Wu, R., Dong, W., Ravikumar, T. S., & Wang, P. (2007). Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages. Molecular medicine, 13(11), 553-560.
WB
Figure 2 CX3CL1 induces MFG-E8 expression in peritoneal macrophages.
Western blotting (representative blots of two separate experiments shown).
Miksa, M., Amin, D., Wu, R., Dong, W., Ravikumar, T. S., & Wang, P. (2007). Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages. Molecular medicine, 13(11), 553-560.
ELISA
Figure 3 Plasma MFG-E8 levels were assessed using ELISA in septic mice 20 h after CLP with or without concurrent treatment with recombinant murine CX3CL1.
ANOVA and Student Newman Keuls' test, n = 5.
Miksa, M., Amin, D., Wu, R., Dong, W., Ravikumar, T. S., & Wang, P. (2007). Fractalkine-induced MFG-E8 leads to enhanced apoptotic cell clearance by macrophages. Molecular medicine, 13(11), 553-560.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgM
- Specificity
- Human MFGE8
- Species Reactivity
- Mouse
- Clone
- 3D10
- Applications
- WB, ELISA, IHC
- Related Disease
- Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The MFGE8 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
- Alternative Names
- BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888
- Gene ID
- 4240
- UniProt ID
- Q08431
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 3D10"
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-657-F(E) | Recombinant Anti-human MFGE8 Antibody Fab Fragment | IP, IF, FuncS | Fab |
| FAMAB-0225CQ-F(E) | Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3); Fab Fragment | ELISA, IF, FuncS | Mouse Fab |
| FAMAB-0365JF-F(E) | Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10); Fab Fragment | IB, WB, ELISA, FuncS | Mouse Fab |
| HPAB-2103-FY-F(E) | Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1); Fab Fragment | IA | Humanized Fab |
| HPAB-2104-FY-F(E) | Mouse Anti-MFGE8 Recombinant Antibody (clone HMFG1); Fab Fragment | IA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-657-S(P) | Recombinant Anti-human MFGE8 Antibody scFv Fragment | WB, FC, FuncS | scFv |
| MHH-657-S(P) | Recombinant Human Anti-human MFGE8 Antibody scFv Fragment | WB, IP, FuncS | scFv |
| FAMAB-0225CQ-S(P) | Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3); scFv Fragment | ELISA, IF, FuncS | Mouse scFv |
| FAMAB-0365JF-S(P) | Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10); scFv Fragment | IB, WB, ELISA, FuncS | Mouse scFv |
| HPAB-2103-FY-S(P) | Human Anti-MFGE8 Recombinant Antibody (clone HuHMFG1); scFv Fragment | IA | Humanized scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-657 | Recombinant Human Anti-human MFGE8 Antibody | IF, ELISA, FuncS | IgG |
| MOB-1240MZ | Recombinant Mouse Anti-Human MFGE8 Antibody (clone FEN56), Biotin-Conjugated | ICC/IF, IHC-P, IP, WB | Mouse antibody |
| FAMAB-0225CQ | Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3) | ELISA, IF, Block, FuncS | Mouse IgG1, κ |
| ZG-0144U | Mouse Anti-MFGE8 Recombinant Antibody (clone 2B2D10) | ELISA, IHC | Mouse IgG2b |
| VS1-YJ106 | Mouse Anti-MFGE8 Recombinant Antibody (clone MFG-06) | IHC, IHC-P | Mouse IgG1 |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0763CL | Mouse Anti-MFGE8 Recombinant Antibody (TAB-0763CL) | ELISA, FuncS, Inhib | Mouse IgG |
| TAB-0764CL | Mouse Anti-MFGE8 Recombinant Antibody (TAB-0764CL) | ELISA, FuncS, Inhib | Mouse IgG |
| TAB-0765CL | Mouse Anti-MFGE8 Recombinant Antibody (TAB-0765CL) | ELISA, FuncS, Inhib | Mouse IgG |
| TAB-0766CL | Mouse Anti-MFGE8 Recombinant Antibody (TAB-0766CL) | ELISA, FuncS, Inhib | Mouse IgG |
| TAB-0763CL-F(E) | Mouse Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0763CL-F(E)) | ELISA | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0768CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0768CL-F(E)) | ELISA | Humanized Fab |
| TAB-0769CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0769CL-F(E)) | ELISA | Humanized Fab |
| TAB-0770CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0770CL-F(E)) | ELISA | Humanized Fab |
| TAB-0771CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0771CL-F(E)) | ELISA | Humanized Fab |
| TAB-0772CL-F(E) | Human Anti-MFGE8 Recombinant Antibody; Fab Fragment (TAB-0772CL-F(E)) | ELISA | Humanized Fab |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC048 | PE-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer | FCM | |
| MHC-LC049 | APC-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer | FCM | |
| MHC-LC050 | BV421-A*02:01/Human BA46 (GLQHWVPEL) MHC Tetramer | FCM | |
| MHC-YF323 | A*02:01/Human BA46 (NLFETPVEA) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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