Provided are fully human monoclonal antibodies that specifically bind to a cell surface receptor, wherein the receptor protein is a Notch1 receptor protein. The antibody can be used for treatment and diagnosis of pathological hyperproliferative oncogenic disorders associated with expression of Notch1 or Notch3 including aberrant activation of each of these receptors.
Figure 1 Binding affinity determination (EC50) in ELISA using different concentrations of purified IgG protein.
Three mAbs binding to Notch 1 ligand binding domain antigen (Alal9-Gln526).
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-660 | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment | ELISA | Human scFv |
HPAB-0044LY-S(P) | Mouse Anti-NOTCH1 Recombinant Antibody; scFv Fragment (HPAB-0044LY-S(P)) | WB | Mouse scfv |
HPAB-AP750-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc133); scFv Fragment | ELISA, FC | Human scFv |
HPAB-AP751-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc155); scFv Fragment | ELISA, FC | Human scFv |
HPAB-AP752-YC-S(P) | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc49); scFv Fragment | ELISA, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-539MZ | Rat Anti-NOTCH1 Recombinant Antibody (TAB-539MZ) | WB, Competition ELISA, Neut | Rat IgG1 |
TAB-540MZ | Rat Anti-NOTCH1 Recombinant Antibody (TAB-540MZ) | WB, Competition ELISA, Neut | Rat IgG1 |
TAB-539MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-539MZ-S(P)) | WB, Competition ELISA | Rat scFv |
TAB-540MZ-S(P) | Rat Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-540MZ-S(P)) | WB, Competition ELISA | Rat scFv |
TAB-543MZ-S(P) | Anti-Human NOTCH1 Recombinant Antibody scFv Fragment (mAb N248A) | ELISA, WB, Luciferase reporter assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-541MZ | Human Anti-NOTCH1 Recombinant Antibody (TAB-541MZ) | Neut, WB | Humanized antibody |
TAB-541MZ-S(P) | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-541MZ-S(P)) | WB, Competition ELISA | Humanized scFv |
TAB-542MZ-S(P) | Human Anti-NOTCH1 Recombinant Antibody; scFv Fragment (TAB-542MZ-S(P)) | WB, Competition ELISA | Humanized scFv |
TAB-544MZ-S(P) | Anti-Human NOTCH1 Recombinant Antibody scFv Fragment (A12.2) | ELISA, WB, Luciferase reporter assay | Humanized antibody |
TAB-544MZ-F(E) | Anti-Human NOTCH1 Recombinant Antibody Fab Fragment (A12.2) | ELISA, WB, Luciferase reporter assay | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-545MZ | Anti-Human NOTCH1 Recombinant Antibody (23814) | ELISA, FuncS, Inhib, WB, FACS | Human antibody |
TAB-546MZ | Anti-Human NOTCH1 Recombinant Antibody (23418.8) | FuncS, Inhib | Human antibody |
TAB-547MZ | Human Anti-NOTCH1 Recombinant Antibody (TAB-547MZ) | Inhib | Human IgG1 |
PABX-152 | Recombinant Human Anti-NRR1 Antibody | ELISA, Neut, FuncS | IgG |
PABX-152-F (E) | Recombinant Human Anti-NRR1 Antibody Fab Fragment | ELISA, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1786CQ | Recombinant Mouse Anti-NOTCH1 Antibody (MHN1-519) | FC, BL | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2473 | Hi-Affi™ Recombinant Rabbit Anti-NOTCH1 Monoclonal Antibody (DS2473AB) | WB, IHC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0078-YC-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone OMP-52M51); Fab Fragment | IHC | Mouse Fab |
NS-060CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2E6); Fab Fragment | FC, IF, ELISA | Mouse Fab |
NS-061CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2G10); Fab Fragment | FC, IF, ELISA | Mouse Fab |
NS-062CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2A11); Fab Fragment | FC, IF, ELISA | Mouse Fab |
HPAB-0044LY-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody; Fab Fragment (HPAB-0044LY-F(E)) | WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-060CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2E6) | FC, IF, ELISA, Inhib, FuncS | Mouse IgG1 |
NS-061CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2G10) | FC, IF, ELISA | Mouse IgG1 |
NS-062CN | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2A11) | FC, IF, ELISA, Inhib | Mouse IgG2b |
NS-063CN-F(E) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2D11); Fab Fragment | FC, IF, ELISA | Mouse Fab |
NS-063CN-S(P) | Mouse Anti-NOTCH1 Recombinant Antibody (clone 2D11); scFv Fragment | FC, IF, ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H11 | Afuco™ Anti-NOTCH1 ADCC Recombinant Antibody (Brontictuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP750-YC | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc133) | ELISA, Block | Human IgG1 |
HPAB-AP751-YC | Human Anti-NOTCH1 Recombinant Antibody (clone hN1wc155) | Block | Human IgG1 |
HPAB-AP753-YC | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc104) | ELISA, FC | Human IgG1 |
HPAB-AP754-YC | Human Anti-NOTCH1 Recombinant Antibody (clone N1wc629) | ELISA | Human IgG1 |
HPAB-AP755-YC | Human Anti-NOTCH1 Recombinant Antibody (clone hN1S3-67) | ELISA, FC | Human IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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