Mouse Anti-PSCA Recombinant Antibody (clone mAb 6F8) (CAT#: HPAB-0288CQ)

This product is a recombinant mouse antibody that can bind to human PSCA with high affinity.


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  • Size:
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  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 A graph showing internalization of the different anti-PSCA monoclonal antibodies (6C3; 6F8; 10A1; 8D11; 5F2; 7A6) in the three cell types, as measured within 1 hour, by the intensity of the Cy3 fluorescence.

Figure 1 A graph showing internalization of the different anti-PSCA monoclonal antibodies (6C3; 6F8; 10A1; 8D11; 5F2; 7A6) in the three cell types, as measured within 1 hour, by the intensity of the Cy3 fluorescence.

FuncS

Figure 2 Shows the growth of PC-3.gDPSCA tumors in mice wherein treatment with anti-PSCA antibodies 6F8, 8D11, or 5F2 was initiated after the tumors had been allowed to grow for 1 week in the mice and had reached a mean 35 tumor volume of approximately 200 mm per group of mice. Antibody administration was biweekly. “RX” under the arrows indicates the time point (day) of intraperitoneal injection of the antibodies into the mice.

Figure 2 Shows the growth of PC-3.gDPSCA tumors in mice wherein treatment with anti-PSCA antibodies 6F8, 8D11, or 5F2 was initiated after the tumors had been allowed to grow for 1 week in the mice and had reached a mean 35 tumor volume of approximately 200 mm per group of mice. Antibody administration was biweekly. “RX” under the arrows indicates the time point (day) of intraperitoneal injection of the antibodies into the mice.


Specifications

  • Immunogen
  • Human PSCA expressed in E.coli
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b
  • Specificity
  • Human PSCA
  • Species Reactivity
  • Human
  • Clone
  • mAb 6F8
  • Applications
  • FC, IHC, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry and Functional Assay. Please see the Published Data for further information.

Target

  • Alternative Names
  • PSCA; prostate stem cell antigen; PRO232

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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