Recombinant Human Anti-RSV F Antibody (14N4) (CAT#: PABC-494)
This product is a recombinant Human antibody that can recognize RSV F. The neutralizing mAb 14N4 interacts with antigenic site II determines.
Specific Inquiry
SPR
Figure 1 Surface plasmon resonance of 14N4 Fabs binding to FFL_001 with calculated KD values displayed.
Colored data points are overlaid with the curve fit line in black. Dotted lines indicate the start of association and dissociation steps.
Mousa, J. J., Sauer, M. F., Sevy, A. M., Finn, J. A., Bates, J. T., Alvarado, G., ... & Correia, B. E. (2016). Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proceedings of the National Academy of Sciences, 113(44), E6849-E6858.
ELISA
Figure 2 ELISA binding curves for human mAb 14N4.
Binding curves for FFL_001 are in red and for RPM-1 are in blue. Binding to MPV F protein is shown in black. EC₅₀ values are displayed for each, in corresponding colors. Error bars indicate 95% confidence intervals.
Mousa, J. J., Sauer, M. F., Sevy, A. M., Finn, J. A., Bates, J. T., Alvarado, G., ... & Correia, B. E. (2016). Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein. Proceedings of the National Academy of Sciences, 113(44), E6849-E6858.
Specifications
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- RSV F
- Species Reactivity
- RSV
- Clone
- 14N4
- Applications
- SPR, ELISA, Neut
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Surface Plasmon Resonance, Neutralization and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- F; Fusion glycoprotein F0; RSV F; Respiratory Syncytial Virus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 14N4"
See other products for "RSV F"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009 | Anti-RSV Recombinant Antibody (Palivizumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-709 | Anti-RSV glycoprotein F Recombinant Antibody (Motavizumab) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| MRO-1209LC | Anti-HRSV F Recombinant Antibody (MEDI-493) | ELISA, Neut, PK | Humanized antibody |
| MRO-1209LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (MEDI-493) | ELISA | Humanized antibody |
| MRO-1209LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (MEDI-493) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-358CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-358CT-S(P)) | ELISA, WB, Neut, IF, FC | Human scFv |
| TAB-361CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-361CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-362CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-362CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-363CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-363CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
| TAB-364CT-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (TAB-364CT-S(P)) | ELISA, WB, Neut, IP | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-878LC | Human Anti-RSV F Recombinant Antibody (MRO-878LC) | ELISA, Neut | Human IgG |
| PABC-276 | Recombinant Mouse Anti-RSV F Antibody (5C4) | ELISA, Neut, DB, FC | Mouse IgG |
| HPAB-0105-WJ | Human Anti-RSV F Recombinant Antibody (HPAB-0105-WJ) | ELISA, WB, Neut, IF, FC, Inhib, PK, IHC, DB | Human IgG |
| PABS-0157 | Human Anti-RSV F Recombinant Antibody (clone C57) | FC, ELISA | Human IgG |
| PABJ-0100 | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6) | ELISA, Neut | Mouse IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-878LC-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (MRO-878LC-S(P)) | ELISA, Neut | Human scFv |
| PSBC-494 | Recombinant Human Anti-RSV F Antibody scFv Fragment (14N4) | ELISA, Neut | Human scFv |
| HPAB-0105-WJ-S(P) | Human Anti-RSV F Recombinant Antibody; scFv Fragment (HPAB-0105-WJ-S(P)) | ELISA, WB | Human scFv |
| PABJ-0100-S(P) | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6); scFv Fragment | ELISA, Neut | Mouse scFv |
| PABJ-0166-S(P) | Human Anti-RSV F Recombinant Antibody (clone RSD5); scFv Fragment | ELISA, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-878LC-F(E) | Human Anti-RSV F Recombinant Antibody; Fab Fragment (MRO-878LC-F(E)) | ELISA, Neut | Human Fab |
| HPAB-0293CQ-F(E) | Human Anti-RSV F Recombinant Antibody; Fab Fragment (HPAB-0293CQ-F(E)) | ELISA, Neut | Human Fab |
| PFBC-276 | Recombinant Mouse Anti-RSV F Antibody Fab Fragment (5C4) | ELISA, Neut | Mouse Fab |
| PFBC-494 | Recombinant Human Anti-RSV F Antibody Fab Fragment (14N4) | ELISA, Neut | Human Fab |
| PABJ-0100-F(E) | Mouse Anti-RSV F Recombinant Antibody (clone R4.C6); Fab fragment | ELISA, Neut | Mouse Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1210LC | Anti-HRSV F Recombinant Antibody (C11) | ELISA | Mouse Antibody |
| MRO-1211LC | Anti-HRSV F Recombinant Antibody (C13) | ELISA | Mouse Antibody |
| MRO-1210LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (C11) | ELISA | Mouse Antibody |
| MRO-1210LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (C11) | ELISA | Mouse Antibody |
| MRO-1211LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (C13) | ELISA | Mouse Antibody |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-009 | Afuco™ Anti-RSV F ADCC Recombinant Antibody (Palivizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-709 | Afuco™ Anti-RSV F ADCC Recombinant Antibody (Motavizumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YC250 | H-2Kd/Respiratory syncytial virus Fusion protein (F) (KYKNAVTEL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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